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bifunctional D-altronate/D-mannonate dehydratase [Shigella flexneri


LOCUS       NP_709762                404 aa            linear   CON 24-AUG-2016
            2a str. 301].
ACCESSION   NP_709762
VERSION     NP_709762.1
DBLINK      BioProject: PRJNA62907
            Assembly: GCF_000006925.2
DBSOURCE    REFSEQ: accession NC_004337.2
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri 2a str. 301
  ORGANISM  Shigella flexneri 2a str. 301
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 404)
  AUTHORS   Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H.,
            Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D.,
            Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K.,
            Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y.,
            Hou,Y. and Yu,J.
  TITLE     Genome sequence of Shigella flexneri 2a: insights into
            pathogenicity through comparison with genomes of Escherichia coli
            K12 and O157
  JOURNAL   Nucleic Acids Res. 30 (20), 4432-4441 (2002)
   PUBMED   12384590
REFERENCE   2  (residues 1 to 404)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 404)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2011) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 404)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2004) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   5  (residues 1 to 404)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2001) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AAN45469.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
                        FGS: First Genome sequenced
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Shigella flexneri 2a str. 301"
                     /strain="301"
                     /serotype="2a"
                     /db_xref="taxon:198214"
     Protein         1..404
                     /product="bifunctional D-altronate/D-mannonate
                     dehydratase"
                     /calculated_mol_wt=45658
     Region          1..404
                     /region_name="PRK15072"
                     /note="D-galactonate dehydratase family protein"
                     /db_xref="CDD:237901"
     Site            order(120,147,149,212,236,238,264,287,314,341)
                     /site_type="active"
                     /note="putative active site pocket [active]"
                     /db_xref="CDD:239438"
     Site            order(212,238,264)
                     /site_type="other"
                     /note="putative metal binding site [ion binding]"
                     /db_xref="CDD:239438"
     CDS             1..404
                     /locus_tag="SF4039"
                     /coded_by="NC_004337.2:4174916..4176130"
                     /note="Code: H; COG: COG1441"
                     /transl_table=11
                     /db_xref="GeneID:1027398"
CONTIG      join(WP_000690944.1:1..404)
ORIGIN      
        1 mkiiaadvfv tcpgrnfvtl kittesglcg lgdatlngre lsvasylkdy lcpqligrda
       61 sriediwqff ykgaywrrgp vtmsaisaid malwdikaka anmplyqllg gasregvmvy
      121 chttgrtide vledyakhqq mgfkairvqc gvpgmqttyg lakgkglaye patkglwpee
      181 qlwssekyld ftpklfeavr nkfgfnehll hdmhhrltpi eaarfgksie dyrlfwmedp
      241 tpaenqecfr lirqhtvtpi avgevfnsiw dckqlieeql igyirttith aggitgmrri
      301 adfaslyqvr tgshgpsdls pvchaaalhf dlwvpnfgvq eymgyseqml evfpyswrfe
      361 egymhpgdep glgisfdekl aakypydpey lpvarledgt llnw