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LOCUS NP_709743 386 aa linear CON 24-AUG-2016 ACCESSION NP_709743 VERSION NP_709743.2 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 386) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 386) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 386) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 386) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 386) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN45450. On Dec 9, 2004 this sequence version replaced NP_709743.1. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..386 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..386 /product="cystathionine gamma-synthase" /calculated_mol_wt=41366 Region 1..386 /region_name="PRK08045" /note="cystathionine gamma-synthase; Provisional" /db_xref="CDD:169194" Site order(29..32,34..35,46,48,74..75,77..78,101,106,109,197, 205,207,224,234,236..237,316) /site_type="other" /note="homodimer interface [polypeptide binding]" /db_xref="CDD:99738" Site order(75..77,101,144,173,195,197..198,207) /site_type="active" /note="substrate-cofactor binding pocket [active]" /db_xref="CDD:99738" Site order(75..77,101,173,176,195,197..198) /site_type="other" /note="pyridoxal 5'-phosphate binding site [chemical binding]" /db_xref="CDD:99738" Site 198 /site_type="active" /note="catalytic residue [active]" /db_xref="CDD:99738" CDS 1..386 /gene="metB" /locus_tag="SF4017" /coded_by="NC_004337.2:4143749..4144909" /note="Code: E; COG: COG0626" /transl_table=11 /db_xref="GeneID:1025177" CONTIG join(WP_005050443.1:1..386) ORIGIN 1 mtrkqatiav rsglnddeqy gcvvppihls stynftgfne prahdysrrg nptrdvvqra 61 laeleggaga vltntgmsai hlvttvflkp gdllvaphdc yggsyrlfds lakrgcyrvl 121 fvdqgdeqal raalaekpkl vlvespsnpl lrvvdiakic hlarevgavs vvdntflspa 181 lqnplalgad lvlhsctkyl nghsdvvagv viakdpdvvt elawwannig vtggafdsyl 241 llrglrtlvp rmelaqrnaq aivkylqtqp lvkklyhpsl penqgheiaa rqqkgfgaml 301 sfeldgdeqt lcrflgglsl ftlaeslggv eslishaatm thagmapear aaagisetll 361 ristgiedge dliadlengf raankg