MULTISPECIES: cystathionine gamma-synthase [Enterobacteriaceae].

LOCUS       WP_005050443             386 aa            linear   BCT 19-JUN-2019
ACCESSION   WP_005050443
VERSION     WP_005050443.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005961.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08045
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..386
                     /gene="metB"
     Protein         1..386
                     /product="cystathionine gamma-synthase"
                     /EC_number="2.5.1.48"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /calculated_mol_wt=41366
     Region          1..386
                     /region_name="PRK08045"
                     /note="cystathionine gamma-synthase; Provisional"
                     /db_xref="CDD:169194"
     Site            order(29..32,34..35,46,48,74..75,77..78,101,106,109,197,
                     205,207,224,234,236..237,316)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99738"
     Site            order(75..77,101,144,173,195,197..198,207)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:99738"
     Site            order(75..77,101,173,176,195,197..198)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99738"
     Site            198
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
ORIGIN      
        1 mtrkqatiav rsglnddeqy gcvvppihls stynftgfne prahdysrrg nptrdvvqra
       61 laeleggaga vltntgmsai hlvttvflkp gdllvaphdc yggsyrlfds lakrgcyrvl
      121 fvdqgdeqal raalaekpkl vlvespsnpl lrvvdiakic hlarevgavs vvdntflspa
      181 lqnplalgad lvlhsctkyl nghsdvvagv viakdpdvvt elawwannig vtggafdsyl
      241 llrglrtlvp rmelaqrnaq aivkylqtqp lvkklyhpsl penqgheiaa rqqkgfgaml
      301 sfeldgdeqt lcrflgglsl ftlaeslggv eslishaatm thagmapear aaagisetll
      361 ristgiedge dliadlengf raankg