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6-phosphofructokinase [Shigella flexneri 2a str. 301].


LOCUS       NP_709721                314 aa            linear   CON 24-AUG-2016
ACCESSION   NP_709721
VERSION     NP_709721.2
DBLINK      BioProject: PRJNA62907
            Assembly: GCF_000006925.2
DBSOURCE    REFSEQ: accession NC_004337.2
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri 2a str. 301
  ORGANISM  Shigella flexneri 2a str. 301
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 314)
  AUTHORS   Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H.,
            Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D.,
            Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K.,
            Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y.,
            Hou,Y. and Yu,J.
  TITLE     Genome sequence of Shigella flexneri 2a: insights into
            pathogenicity through comparison with genomes of Escherichia coli
            K12 and O157
  JOURNAL   Nucleic Acids Res. 30 (20), 4432-4441 (2002)
   PUBMED   12384590
REFERENCE   2  (residues 1 to 314)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2011) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 314)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-AUG-2011) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   4  (residues 1 to 314)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2004) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
  REMARK    Sequence update by submitter
REFERENCE   5  (residues 1 to 314)
  AUTHORS   Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B.,
            Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y.,
            Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y.,
            Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2001) State Key Laboratory for Moleclular
            Virology and Genetic Engineering, Microbial Genome Center of
            Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA,
            Beijing 100176, P.R.China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AAN45428.
            
            On Dec 9, 2004 this sequence version replaced NP_709721.1.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
                        FGS: First Genome sequenced
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Shigella flexneri 2a str. 301"
                     /strain="301"
                     /serotype="2a"
                     /db_xref="taxon:198214"
     Protein         1..314
                     /product="6-phosphofructokinase"
                     /calculated_mol_wt=34072
     Region          2..313
                     /region_name="PRK03202"
                     /note="ATP-dependent 6-phosphofructokinase"
                     /db_xref="CDD:235111"
     Site            order(6,36,67,98..100,102..103,120,122,124,164..166,217,
                     244,247)
                     /site_type="active"
                     /db_xref="CDD:238388"
     Site            order(6,36,67,98..100,102..103)
                     /site_type="other"
                     /note="ADP/pyrophosphate binding site [chemical binding]"
                     /db_xref="CDD:238388"
     Site            order(16,20,49,54,57,130,142,146,149,177..178,180,208,
                     256..257,261,268,283,312..314)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:238388"
     Site            order(16,20,49..50,53..54,149,180,182,206,208..210)
                     /site_type="active"
                     /note="allosteric effector site [active]"
                     /db_xref="CDD:238388"
     Site            order(120,122,124,157,164..166,217,238,244,247)
                     /site_type="other"
                     /note="fructose-1,6-bisphosphate binding site"
                     /db_xref="CDD:238388"
     CDS             1..314
                     /gene="pfkA"
                     /locus_tag="SF3994"
                     /coded_by="NC_004337.2:4122552..4123496"
                     /note="Code: G; COG: COG0205"
                     /transl_table=11
                     /db_xref="GeneID:1026924"
CONTIG      join(WP_005089906.1:1..314)
ORIGIN      
        1 mltsggdapg mnaairgvvr salteglevm giydgylgly edrmvqldry svsdminrgg
       61 tflgsarfpe frdenirava ienlkkrgid alvviggdgs ymgamrltem gfpciglpgt
      121 idndikgtdy tigfftalst vveaidrlrd tssshqrisv vevmgrycgd ltlaaaiagg
      181 cefvvvpeve fsredlvnei kagiakgkkh aivaitehmc dvdelahfie ketgretrat
      241 vlghiqrggs pvpydrilas rmgayaidll lagyggrcvg iqneqlvhhd iidaienmkr
      301 pfkgdwldca kkly