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LOCUS NP_708521 336 aa linear CON 24-AUG-2016 ACCESSION NP_708521 VERSION NP_708521.2 DBLINK BioProject: PRJNA62907 Assembly: GCF_000006925.2 DBSOURCE REFSEQ: accession NC_004337.2 KEYWORDS RefSeq. SOURCE Shigella flexneri 2a str. 301 ORGANISM Shigella flexneri 2a str. 301 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella. REFERENCE 1 (residues 1 to 336) AUTHORS Jin,Q., Yuan,Z., Xu,J., Wang,Y., Shen,Y., Lu,W., Wang,J., Liu,H., Yang,J., Yang,F., Zhang,X., Zhang,J., Yang,G., Wu,H., Qu,D., Dong,J., Sun,L., Xue,Y., Zhao,A., Gao,Y., Zhu,J., Kan,B., Ding,K., Chen,S., Cheng,H., Yao,Z., He,B., Chen,R., Ma,D., Qiang,B., Wen,Y., Hou,Y. and Yu,J. TITLE Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157 JOURNAL Nucleic Acids Res. 30 (20), 4432-4441 (2002) PUBMED 12384590 REFERENCE 2 (residues 1 to 336) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (26-AUG-2011) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (residues 1 to 336) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (03-AUG-2011) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 4 (residues 1 to 336) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (06-DEC-2004) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China REMARK Sequence update by submitter REFERENCE 5 (residues 1 to 336) AUTHORS Jin,Q., Shen,Y., Wang,J.H., Liu,H., Yang,J., Yang,F., Zhang,X.B., Zhang,J.Y., Yang,G.W., Wu,H.T., Dong,J., Sun,L.L., Xue,Y., Zhao,A.L., Gao,Y.S., Zhu,J.P., Chen,S.X., Yao,Z.J., Wang,Y., Lu,W.C., Qiang,B.Q., Wen,Y.M. and Hou,Y.D. TITLE Direct Submission JOURNAL Submitted (21-MAY-2001) State Key Laboratory for Moleclular Virology and Genetic Engineering, Microbial Genome Center of Chinese Ministry of Public Health, 6 Rongjing Eastern Street, BDA, Beijing 100176, P.R.China COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence is identical to AAN44228. On Dec 9, 2004 this sequence version replaced NP_708521.1. RefSeq Category: Reference Genome CLI: Clinical Isolate FGS: First Genome sequenced Method: conceptual translation. FEATURES Location/Qualifiers source 1..336 /organism="Shigella flexneri 2a str. 301" /strain="301" /serotype="2a" /db_xref="taxon:198214" Protein 1..336 /product="ascBF operon repressor" /calculated_mol_wt=36694 Region 2..69 /region_name="HTH_LACI" /note="helix_turn _helix lactose operon repressor; smart00354" /db_xref="CDD:197675" Site order(13..17,19..20,23,28..29,32,45,48,51..52,54..55) /site_type="DNA binding" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:143331" Site 45..54 /site_type="active" /note="domain linker motif [active]" /db_xref="CDD:143331" Region 61..329 /region_name="PBP1_GalS-like" /note="ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; cd06270" /db_xref="CDD:380494" Site order(61,68,76,81,84,93..96,98,112,116,224..225,257, 283..284) /site_type="other" /note="dimer interface (closed form) [polypeptide binding]" /db_xref="CDD:380494" Site order(75,124,197,222,248,276) /site_type="other" /note="ligand binding site [chemical binding]" /db_xref="CDD:380494" CDS 1..336 /gene="ascG" /locus_tag="SF2737" /coded_by="complement(NC_004337.2:2811926..2812936)" /note="Code: K; COG: COG1609" /transl_table=11 /db_xref="GeneID:1027456" CONTIG join(WP_005051459.1:1..336) ORIGIN 1 mttmlevakr agvskatvsr vlsgngyvsq etkdrvfqav eessyrpnll arnlsakstq 61 tlglvvtntl yhgiyfsell fhaarmaeek grqllladgk hsaeeerqai qylldlrcda 121 imiyprflsv deiddiidah sqpimvlnrr lrnnsshsvw cdhkqtsfna vaelinaghq 181 eiafltgsmd sptsierlag ykdalsqhgi alnekliang kwtpasgaeg vetllergak 241 fsalvasndd maigaikalh ergvavpeqv svigfddiai apyivpalss vkipvtemiq 301 eiigrlifml dggdfsppkt fsgklirrds lialsr