MULTISPECIES: DNA-binding transcriptional regulator AscG

LOCUS       WP_005051459             336 aa            linear   BCT 17-NOV-2023
            [Shigella].
ACCESSION   WP_005051459
VERSION     WP_005051459.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 336)
  AUTHORS   Hall,B.G. and Xu,L.
  TITLE     Nucleotide sequence, function, activation, and evolution of the
            cryptic asc operon of Escherichia coli K12
  JOURNAL   Mol. Biol. Evol. 9 (4), 688-706 (1992)
   PUBMED   1630307
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011140
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..336
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..336
                     /gene="ascG"
     Protein         1..336
                     /product="DNA-binding transcriptional regulator AscG"
                     /calculated_mol_wt=36694
     Region          2..69
                     /region_name="HTH_LACI"
                     /note="helix_turn _helix lactose operon repressor;
                     smart00354"
                     /db_xref="CDD:197675"
     Site            order(13..17,19..20,23,28..29,32,45,48,51..52,54..55)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143331"
     Site            45..54
                     /site_type="active"
                     /note="domain linker motif [active]"
                     /db_xref="CDD:143331"
     Region          61..329
                     /region_name="PBP1_GalS-like"
                     /note="ligand binding domain of DNA transcription
                     iso-repressor GalS, which is one of two regulatory
                     proteins involved in galactose transport and metabolism;
                     cd06270"
                     /db_xref="CDD:380494"
     Site            order(61,68,76,81,84,93..96,98,112,116,224..225,257,
                     283..284)
                     /site_type="other"
                     /note="dimer interface (closed form) [polypeptide
                     binding]"
                     /db_xref="CDD:380494"
     Site            order(75,124,197,222,248,276)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:380494"
ORIGIN      
        1 mttmlevakr agvskatvsr vlsgngyvsq etkdrvfqav eessyrpnll arnlsakstq
       61 tlglvvtntl yhgiyfsell fhaarmaeek grqllladgk hsaeeerqai qylldlrcda
      121 imiyprflsv deiddiidah sqpimvlnrr lrnnsshsvw cdhkqtsfna vaelinaghq
      181 eiafltgsmd sptsierlag ykdalsqhgi alnekliang kwtpasgaeg vetllergak
      241 fsalvasndd maigaikalh ergvavpeqv svigfddiai apyivpalss vkipvtemiq
      301 eiigrlifml dggdfsppkt fsgklirrds lialsr