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penicillin-binding protein 2B [Listeria monocytogenes EGD-e].


LOCUS       NP_465563                751 aa            linear   CON 28-AUG-2016
ACCESSION   NP_465563
VERSION     NP_465563.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 751)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 751)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 751)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 751)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 751)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAD00117.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..751
                     /product="penicillin-binding protein 2B"
                     /calculated_mol_wt=81768
     Region          1..590
                     /region_name="FtsI"
                     /note="Cell division protein FtsI, peptidoglycan
                     transpeptidase (Penicillin-binding protein 2) [Cell cycle
                     control, cell division, chromosome partitioning, Cell
                     wall/membrane/envelope biogenesis]; COG0768"
                     /db_xref="CDD:440531"
     Region          603..657
                     /region_name="PASTA_Pbp2x-like_1"
                     /note="PASTA domain of PBP2x-like proteins, first repeat.
                     Penicillin-binding proteins (PBPs) are the major targets
                     for beta-lactam antibiotics, like penicillins and
                     cephalosporins. Beta-lactam antibiotics specifically
                     inhibit transpeptidase activity by...; cd06576"
                     /db_xref="CDD:119327"
     Region          603..656
                     /region_name="PASTA domain"
                     /note="PASTA domain [structural motif]"
                     /db_xref="CDD:275384"
     Region          661..714
                     /region_name="PASTA_Pbp2x-like_2"
                     /note="PASTA domain of PBP2x-like proteins, second repeat.
                     Penicillin-binding proteins (PBPs) are the major targets
                     for beta-lactam antibiotics, like penicillins and
                     cephalosporins. Beta-lactam antibiotics specifically
                     inhibit transpeptidase activity by...; cd06575"
                     /db_xref="CDD:119326"
     Region          661..713
                     /region_name="PASTA domain"
                     /note="PASTA domain [structural motif]"
                     /db_xref="CDD:275384"
     CDS             1..751
                     /gene="pbpB"
                     /locus_tag="lmo2039"
                     /coded_by="complement(NC_003210.1:2121483..2123738)"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /transl_table=11
                     /db_xref="GeneID:984823"
CONTIG      join(WP_003731976.1:1..751)
ORIGIN      
        1 mkrrignmrr galvlfifft ilfllvsgrf lylqitgean gvplaakask qhlkssvlea
       61 krgsildrkg evlaedtasy tvaavvsdkl skttknpmrv vdeektaril akyipmdesd
      121 ildklhekgk yqvefgaagk nistetkaki dkenlpgief trqserfypn gtfatqligf
      181 aqqeeeknat vlegkmgies ryndiltgkn gkidystdrm gyilpnsknk vteakdgkdi
      241 tltldkkiqt fledtmttvd akykpknmma vvadpktgei laisqrpsfn padrstitgn
      301 sssiwqdlpv eyayepgsvm kiislasaid tnaynaneyy qsgsykvgdi aihdhnngng
      361 wgsityregv erssnvafak llnkmgtdtf ktyldkfgfg kktgialpne tsgkilynyp
      421 iekvttvfgq gttvsmmqmi qaasaiasdg tmkepyvvss vkdpntgeet dtktkiagkp
      481 isaetakktr delknvisge hgtgklyaip gydvagktgt sqipdpktgk ymtgadnyif
      541 sflgmapadn pelviyvtmq qpqlsgsqtg geavsevfnp vmknslqymn ikpgdaekla
      601 sekvpvlagk kvdeakkivk dkglepivvg ngkkivqqlp qanaeimqgq kvilmtdgdm
      661 tapdmvtwsk ddalkvseit gipfefsgng yvksqsvsag svinsetkmk itlappeeis
      721 afnqnhdqdt aeknkkatdi qenagigdll n