multidrug transporter [Listeria monocytogenes EGD-e].

LOCUS       NP_465371                456 aa            linear   CON 28-AUG-2016
ACCESSION   NP_465371
VERSION     NP_465371.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 456)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 456)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 456)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 456)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 456)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAC99924.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..456
                     /product="multidrug transporter"
                     /calculated_mol_wt=49525
     Region          1..446
                     /region_name="PRK01766"
                     /note="multidrug efflux protein; Reviewed"
                     /db_xref="CDD:234981"
     Site            order(255,259,285,288,367,371,398,423,427)
                     /site_type="other"
                     /note="cation binding site [ion binding]"
                     /db_xref="CDD:240536"
     CDS             1..456
                     /locus_tag="lmo1846"
                     /coded_by="NC_003210.1:1922439..1923809"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /note="NorM; MdtK; functions as a Na(+)/drug antiporter;
                     inactivation in Vibrio cholerae results in susceptibility
                     to fluoroquinolones"
                     /transl_table=11
                     /db_xref="GeneID:985857"
CONTIG      join(WP_003724070.1:1..456)
ORIGIN      
        1 mqqtvtygak wkqfltiftp ivitqltlfs mtffdttmsg nysnqalagv aigssfwapv
       61 naafsgllma itpiiaqlig akkekqvknt vhnglyialf lafililinf lvvpmilthm
      121 pvtaevadia rhflngicig ipaffisail rsfidslglt rvtmlitlct vpfniflnyc
      181 fifgnfgfpe mggagsgyat gitywlvvlv sviliqtqtr lrkfgvfkgl talrfskike
      241 iigigvpngl tilfetsifs avtilmgafg tetiaahqsa nsvctllyaf plsvastlti
      301 lggyetgakr lkdakqyrhi gmaaailigc vngailfffr diiagfytnd palsnlimhf
      361 lvyailfqfa davlspvlga lrgykdvtvt sivafisywl iglpvgygls ftnlgpfgyw
      421 iglstglfva afilsirvrk teqklsfntk daeisn