2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate

LOCUS       NP_465200                580 aa            linear   CON 28-AUG-2016
            synthase [Listeria monocytogenes EGD-e].
ACCESSION   NP_465200
VERSION     NP_465200.1
DBLINK      BioProject: PRJNA61583
            Assembly: GCF_000196035.1
DBSOURCE    REFSEQ: accession NC_003210.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes EGD-e
  ORGANISM  Listeria monocytogenes EGD-e
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 580)
  AUTHORS   Toledo-Arana,A., Dussurget,O., Nikitas,G., Sesto,N.,
            Guet-Revillet,H., Balestrino,D., Loh,E., Gripenland,J., Tiensuu,T.,
            Vaitkevicius,K., Barthelemy,M., Vergassola,M., Nahori,M.A.,
            Soubigou,G., Regnault,B., Coppee,J.Y., Lecuit,M., Johansson,J. and
            Cossart,P.
  TITLE     The Listeria transcriptional landscape from saprophytism to
            virulence
  JOURNAL   Nature 459 (7249), 950-956 (2009)
   PUBMED   19448609
REFERENCE   2  (residues 1 to 580)
  AUTHORS   Chatterjee,S.S., Hossain,H., Otten,S., Kuenne,C., Kuchmina,K.,
            Machata,S., Domann,E., Chakraborty,T. and Hain,T.
  TITLE     Intracellular gene expression profile of Listeria monocytogenes
  JOURNAL   Infect. Immun. 74 (2), 1323-1338 (2006)
   PUBMED   16428782
REFERENCE   3  (residues 1 to 580)
  AUTHORS   Glaser,P., Frangeul,L., Buchrieser,C., Amend,A., Baquero,F.,
            Berche,P., Bloecker,H., Brandt,P., Chakraborty,T., Charbit,A.,
            Chetouani,F., Couve,E., de Daruvar,A., Dehoux,P., Domann,E.,
            Dominguez-Bernal,G., Duchaud,E., Durand,L., Dussurget,O.,
            Entian,K.-D., Fsihi,H., Garcia-Del Portillo,F., Garrido,P.,
            Gautier,L., Goebel,W., Gomez-Lopez,N., Hain,T., Hauf,J.,
            Jackson,D., Jones,L.-M., Karst,U., Kreft,J., Kuhn,M., Kunst,F.,
            Kurapkat,G., Madueno,E., Maitournam,A., Mata Vicente,J., Ng,E.,
            Nordsiek,G., Novella,S., de Pablos,B., Perez-Diaz,J.-C., Remmel,B.,
            Rose,M., Rusniok,C., Schlueter,T., Simoes,N., Tierrez,A.,
            Vazquez-Boland,J.-A., Voss,H., Wehland,J. and Cossart,P.
  TITLE     Comparative genomics of Listeria species
  JOURNAL   Science 294 (5543), 849-852 (2001)
   PUBMED   11679669
REFERENCE   4  (residues 1 to 580)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 580)
  AUTHORS   Glaser,P., Frangeul,L. and Rusniok,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUN-2001) Glaser P., Institut Pasteur, Genomique des
            Microorganismes Pathogenes, 25 rue du Docteur Roux, 75724 Paris
            Cedex 15, FRANCE
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from CAC99753.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..580
                     /organism="Listeria monocytogenes EGD-e"
                     /strain="EGD-e"
                     /db_xref="taxon:169963"
     Protein         1..580
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylate synthase"
                     /EC_number="4.1.1.71"
                     /calculated_mol_wt=64555
     Region          3..576
                     /region_name="MenD"
                     /note="2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylate synthase [Coenzyme transport and metabolism];
                     COG1165"
                     /db_xref="CDD:440779"
     CDS             1..580
                     /gene="menD"
                     /locus_tag="lmo1675"
                     /coded_by="complement(NC_003210.1:1728653..1730395)"
                     /experiment="EXISTENCE:[PMID:19448609]"
                     /note="SEPHCHC synthase; forms
                     5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-
                     carboxylate from 2-oxoglutarate and isochorismate in
                     menaquinone biosynthesis"
                     /transl_table=11
                     /db_xref="GeneID:985654"
CONTIG      join(WP_010989780.1:1..580)
ORIGIN      
        1 mtnheqvltd ylaafieelv qagvkeaiis pgsrstplal mmaehpilki yvdvdersag
       61 ffalglakas krpvvllcts gtaaanyfpa vaeanlsqip livltadrph elrnvgapqa
      121 mdqlhlygsh vkdftdmalp enseemlrya kwhgsravdi amktprgpvh lnfplreplv
      181 pilepspfta tgkkhhhvhi yythevldds siqkmvtect gkkgvfvvgp idkkeleqpm
      241 vdlakklgwp iladplsglr sygaldevvi dqydaflkea eimdkltpev virfgsmpvs
      301 kplknwleql sdirfyvvdp gaawkdpika vtdmihcder flldimqqnm pddakdaawl
      361 srwtsynkva reivlaeman ttileegkiv aelrrllpek aglfignsmp irdvdtyfsq
      421 idkkikmlan rgangidgvv ssalgasvvf qpmflligdl sfyhdmngll makkykmnlt
      481 ivivnndggg ifsflpqane pkyfeslfgt steldfrfaa afydadyhet qsvdeleeai
      541 dkasyhkgld iievktnrhe nkanhqalwa kiadalkaln