2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid

LOCUS       WP_010989780             580 aa            linear   BCT 04-JUN-2024
            synthase [Listeria monocytogenes].
ACCESSION   WP_010989780
VERSION     WP_010989780.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 580)
  AUTHORS   Jiang,M., Cao,Y., Guo,Z.F., Chen,M., Chen,X. and Guo,Z.
  TITLE     Menaquinone biosynthesis in Escherichia coli: identification of
            2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a
            novel intermediate and re-evaluation of MenD activity
  JOURNAL   Biochemistry 46 (38), 10979-10989 (2007)
   PUBMED   17760421
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00173.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..580
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..580
                     /gene="menD"
     Protein         1..580
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /EC_number="2.2.1.9"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070204 -
                     2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylic-acid synthase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=64555
     Region          3..576
                     /region_name="MenD"
                     /note="2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylate synthase [Coenzyme transport and metabolism];
                     COG1165"
                     /db_xref="CDD:440779"
ORIGIN      
        1 mtnheqvltd ylaafieelv qagvkeaiis pgsrstplal mmaehpilki yvdvdersag
       61 ffalglakas krpvvllcts gtaaanyfpa vaeanlsqip livltadrph elrnvgapqa
      121 mdqlhlygsh vkdftdmalp enseemlrya kwhgsravdi amktprgpvh lnfplreplv
      181 pilepspfta tgkkhhhvhi yythevldds siqkmvtect gkkgvfvvgp idkkeleqpm
      241 vdlakklgwp iladplsglr sygaldevvi dqydaflkea eimdkltpev virfgsmpvs
      301 kplknwleql sdirfyvvdp gaawkdpika vtdmihcder flldimqqnm pddakdaawl
      361 srwtsynkva reivlaeman ttileegkiv aelrrllpek aglfignsmp irdvdtyfsq
      421 idkkikmlan rgangidgvv ssalgasvvf qpmflligdl sfyhdmngll makkykmnlt
      481 ivivnndggg ifsflpqane pkyfeslfgt steldfrfaa afydadyhet qsvdeleeai
      541 dkasyhkgld iievktnrhe nkanhqalwa kiadalkaln