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LOCUS NP_252916 1438 aa linear CON 24-JAN-2019 ACCESSION NP_252916 VERSION NP_252916.1 DBLINK BioProject: PRJNA57945 Assembly: GCF_000006765.1 DBSOURCE REFSEQ: accession NC_002516.2 KEYWORDS RefSeq. SOURCE Pseudomonas aeruginosa PAO1 ORGANISM Pseudomonas aeruginosa PAO1 Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. REFERENCE 1 (residues 1 to 1438) AUTHORS Winsor,G.L., Van Rossum,T., Lo,R., Khaira,B., Whiteside,M.D., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes JOURNAL Nucleic acids Res. 37 (DATABASE ISSUE), D483-D488 (2009) PUBMED 18978025 REFERENCE 2 (residues 1 to 1438) AUTHORS Cirz,R.T., O'Neill,B.M., Hammond,J.A., Head,S.R. and Romesberg,F.E. TITLE Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin JOURNAL J. Bacteriol. 188 (20), 7101-7110 (2006) PUBMED 17015649 REFERENCE 3 (residues 1 to 1438) AUTHORS Palmer,K.L., Mashburn,L.M., Singh,P.K. and Whiteley,M. TITLE Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology JOURNAL J. Bacteriol. 187 (15), 5267-5277 (2005) PUBMED 16030221 REFERENCE 4 (residues 1 to 1438) AUTHORS Salunkhe,P., Smart,C.H., Morgan,J.A., Panagea,S., Walshaw,M.J., Hart,C.A., Geffers,R., Tummler,B. and Winstanley,C. TITLE A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance JOURNAL J. Bacteriol. 187 (14), 4908-4920 (2005) PUBMED 15995206 REFERENCE 5 (residues 1 to 1438) AUTHORS Filiatrault,M.J., Wagner,V.E., Bushnell,D., Haidaris,C.G., Iglewski,B.H. and Passador,L. TITLE Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa JOURNAL Infect. Immun. 73 (6), 3764-3772 (2005) PUBMED 15908409 REFERENCE 6 (residues 1 to 1438) AUTHORS Rasmussen,T.B., Bjarnsholt,T., Skindersoe,M.E., Hentzer,M., Kristoffersen,P., Kote,M., Nielsen,J., Eberl,L. and Givskov,M. TITLE Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector JOURNAL J. Bacteriol. 187 (5), 1799-1814 (2005) PUBMED 15716452 REFERENCE 7 (residues 1 to 1438) AUTHORS Winsor,G.L., Lo,R., Sui,S.J., Ung,K.S., Huang,S., Cheng,D., Ching,W.K., Hancock,R.E. and Brinkman,F.S. TITLE Pseudomonas aeruginosa Genome Database and PseudoCap: facilitating community-based, continually updated, genome annotation JOURNAL Nucleic acids Res. 33 (DATABASE ISSUE), D338-D343 (2005) PUBMED 15608211 REFERENCE 8 (residues 1 to 1438) AUTHORS Wagner,V.E., Bushnell,D., Passador,L., Brooks,A.I. and Iglewski,B.H. TITLE Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment JOURNAL J. Bacteriol. 185 (7), 2080-2095 (2003) PUBMED 12644477 REFERENCE 9 (residues 1 to 1438) AUTHORS Schuster,M., Lostroh,C.P., Ogi,T. and Greenberg,E.P. TITLE Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis JOURNAL J. Bacteriol. 185 (7), 2066-2079 (2003) PUBMED 12644476 REFERENCE 10 (residues 1 to 1438) AUTHORS Stover,C.K., Pham,X.Q., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R., Smith,K., Spencer,D., Wong,G.K., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E., Lory,S. and Olson,M.V. TITLE Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen JOURNAL Nature 406 (6799), 959-964 (2000) PUBMED 10984043 REFERENCE 11 (residues 1 to 1438) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (06-OCT-2010) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 12 (residues 1 to 1438) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (08-SEP-2010) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 13 (residues 1 to 1438) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (02-OCT-2008) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK protein update by submitter REFERENCE 14 (residues 1 to 1438) AUTHORS Winsor,G.L., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (05-JUL-2006) Department of Molecular Biology and Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REMARK Sequence update by submitter REFERENCE 15 (residues 1 to 1438) AUTHORS Ung,K.S., Hancock,R.E. and Brinkman,F.S. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (04-FEB-2003) Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Dr., Burnaby, British Columbia V5A 1S6, Canada REFERENCE 16 (residues 1 to 1438) AUTHORS Stover,C.K., Pham,X.-Q.T., Erwin,A.L., Mizoguchi,S.D., Warrener,P., Hickey,M.J., Brinkman,F.S.L., Hufnagle,W.O., Kowalik,D.J., Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R.M., Smith,K.A., Spencer,D.H., Wong,G.K.-S., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H., Hancock,R.E.W., Lory,S. and Olson,M.V. CONSRTM Pseudomonas aeruginosa Community Annotation Project (PseudoCap) TITLE Direct Submission JOURNAL Submitted (16-MAY-2000) Department of Medicine and Genetics, University of Washington Genome Center, University Of Washington, Box 352145, Seattle, WA 98195, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AAG07614. Method: conceptual translation. FEATURES Location/Qualifiers source 1..1438 /organism="Pseudomonas aeruginosa PAO1" /strain="PAO1" /db_xref="taxon:208964" Protein 1..1438 /product="dihydroaeruginoic acid synthetase" /calculated_mol_wt=156292 Region <4..86 /region_name="AcpA" /note="Acyl carrier protein/domain [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; COG3433" /db_xref="CDD:442659" Region 84..1396 /region_name="EntF" /note="seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism]; COG1020" /db_xref="CDD:440643" CDS 1..1438 /gene="pchE" /locus_tag="PA4226" /coded_by="complement(NC_002516.2:4736795..4741111)" /note="Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)" /transl_table=11 /db_xref="GeneID:880048" CONTIG join(WP_003148110.1:1..1438) ORIGIN 1 mdlppdsrta lrdwlteqla dllgepladv raladdddll gcgldsirlm ylqerlrarg 61 stldfaqlaq rpclgawldl lacadrlsap atvalptaqd rdqpfelssv qqaywlgrga 121 gevlgnvsch aflefrtrdv dpqrlaaaae cvrqrhpmlr arfldgrqqi lptpplscfd 181 lqdwrtlqvd eaerdwqalr dwraheclav ergqvfllgl vrmpggedrl wlsldllaad 241 veslrlllae lgvaylaper laeppalhfa dylahraaqr aeaaarardy wlerlprlpd 301 apalplacap esirqprtrr lafqlsages rrlerlaaqh gvtlssvfgc afalvlarws 361 esaefllnvp lfdrhaddpr igeviadftt llllecrmqa gvsfaeavks fqrnlhgaid 421 haafpalevl rearrqgqpr sapvvfasnl geegfvpaaf rdafgdlhdm lsqtpqvwld 481 hqlyrvgdgi llawdsvvgl fpeglpetmf eayvgllqrl cdsawgqpad lplpwaqqar 541 rallngqpac atartlhrdf flraaeapda dallyrdqrv trgelaeral riagglreag 601 vrpgdavevs lprgpqqvaa vfgvlaagac yvpldidqpp arrrlieeaa gvclaiteed 661 dpqalpprld vqrllrgpal aapvplapqa sayviytsgs tgvpkgvevs haaaintida 721 lldllrvnas drllavsald fdlsvfdlfg glgagaslvl paqeqardaa awaeaiqrha 781 vslwnsapal lemalslpas qadyrslrav llsgdwvald lpgrlrprca egcrlhvlgg 841 ateagiwsnl qsvdtvpphw rsipygrplp gqayrvvdth grdvpdlvvg elwiggasla 901 rgyrndpels arrfvhdaqg rwyrtgdrgr ywgdgtlefl grvdqqvkvr gqrielgeve 961 aalcaqagve sacaavlggg vaslgavlvp rlapraegsm dlpaaqpfag laeaeavltr 1021 eilgalleap lelddglrrr wldwladsaa salpsldeal rrlgwqaagl tamgnalrgl 1081 lageqapaal lldpwlapqa vaarlpdgre alarllealp tpaagerlrv avldtraglw 1141 ldqgmasllr pgleltlfer srvlldaaat rlperivvqa lddgllpaeh lgrydrvisf 1201 aalhayeasr eglalaaall rpqgrlllvd llcesplall gaallddrpl rlaelpslla 1261 dlaaaglapr clwrserial vealapglgl daaalqagle qrlpqamrpe rlwclpslpl 1321 ngngkvdrrr laesmtralg ecrhepsaee pleaheqala ecweavlkrp vrrreasffs 1381 lggdsllatr llagirerfg vrlgmadfyr qptlaglarh lqvqtveiee tqleegvl