pyochelin non-ribosomal peptide synthetase PchE [Pseudomonas

LOCUS       WP_003148110            1438 aa            linear   BCT 11-OCT-2023
            aeruginosa].
ACCESSION   WP_003148110
VERSION     WP_003148110.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 1438)
  AUTHORS   Chen,L., Yang,J., Yu,J., Yao,Z., Sun,L., Shen,Y. and Jin,Q.
  TITLE     VFDB: a reference database for bacterial virulence factors
  JOURNAL   Nucleic Acids Res 33 (Database issue), D325-D328 (2005)
   PUBMED   15608208
REFERENCE   2  (residues 1 to 1438)
  AUTHORS   Quadri,L.E., Keating,T.A., Patel,H.M. and Walsh,C.T.
  TITLE     Assembly of the Pseudomonas aeruginosa nonribosomal peptide
            siderophore pyochelin: In vitro reconstitution of aryl-4,
            2-bisthiazoline synthetase activity from PchD, PchE, and PchF
  JOURNAL   Biochemistry 38 (45), 14941-14954 (1999)
   PUBMED   10555976
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012851
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1438
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..1438
                     /gene="pchE"
     Protein         1..1438
                     /product="pyochelin non-ribosomal peptide synthetase PchE"
                     /GO_function="GO:1904091 - non-ribosomal peptide
                     synthetase activity [Evidence IEA]"
                     /calculated_mol_wt=156292
     Region          <4..86
                     /region_name="AcpA"
                     /note="Acyl carrier protein/domain [Lipid transport and
                     metabolism, Secondary metabolites biosynthesis, transport
                     and catabolism]; COG3433"
                     /db_xref="CDD:442659"
     Region          84..1396
                     /region_name="EntF"
                     /note="seryl-AMP synthase component of non-ribosomal
                     peptide synthetase [Secondary metabolites biosynthesis,
                     transport and catabolism]; COG1020"
                     /db_xref="CDD:440643"
ORIGIN      
        1 mdlppdsrta lrdwlteqla dllgepladv raladdddll gcgldsirlm ylqerlrarg
       61 stldfaqlaq rpclgawldl lacadrlsap atvalptaqd rdqpfelssv qqaywlgrga
      121 gevlgnvsch aflefrtrdv dpqrlaaaae cvrqrhpmlr arfldgrqqi lptpplscfd
      181 lqdwrtlqvd eaerdwqalr dwraheclav ergqvfllgl vrmpggedrl wlsldllaad
      241 veslrlllae lgvaylaper laeppalhfa dylahraaqr aeaaarardy wlerlprlpd
      301 apalplacap esirqprtrr lafqlsages rrlerlaaqh gvtlssvfgc afalvlarws
      361 esaefllnvp lfdrhaddpr igeviadftt llllecrmqa gvsfaeavks fqrnlhgaid
      421 haafpalevl rearrqgqpr sapvvfasnl geegfvpaaf rdafgdlhdm lsqtpqvwld
      481 hqlyrvgdgi llawdsvvgl fpeglpetmf eayvgllqrl cdsawgqpad lplpwaqqar
      541 rallngqpac atartlhrdf flraaeapda dallyrdqrv trgelaeral riagglreag
      601 vrpgdavevs lprgpqqvaa vfgvlaagac yvpldidqpp arrrlieeaa gvclaiteed
      661 dpqalpprld vqrllrgpal aapvplapqa sayviytsgs tgvpkgvevs haaaintida
      721 lldllrvnas drllavsald fdlsvfdlfg glgagaslvl paqeqardaa awaeaiqrha
      781 vslwnsapal lemalslpas qadyrslrav llsgdwvald lpgrlrprca egcrlhvlgg
      841 ateagiwsnl qsvdtvpphw rsipygrplp gqayrvvdth grdvpdlvvg elwiggasla
      901 rgyrndpels arrfvhdaqg rwyrtgdrgr ywgdgtlefl grvdqqvkvr gqrielgeve
      961 aalcaqagve sacaavlggg vaslgavlvp rlapraegsm dlpaaqpfag laeaeavltr
     1021 eilgalleap lelddglrrr wldwladsaa salpsldeal rrlgwqaagl tamgnalrgl
     1081 lageqapaal lldpwlapqa vaarlpdgre alarllealp tpaagerlrv avldtraglw
     1141 ldqgmasllr pgleltlfer srvlldaaat rlperivvqa lddgllpaeh lgrydrvisf
     1201 aalhayeasr eglalaaall rpqgrlllvd llcesplall gaallddrpl rlaelpslla
     1261 dlaaaglapr clwrserial vealapglgl daaalqagle qrlpqamrpe rlwclpslpl
     1321 ngngkvdrrr laesmtralg ecrhepsaee pleaheqala ecweavlkrp vrrreasffs
     1381 lggdsllatr llagirerfg vrlgmadfyr qptlaglarh lqvqtveiee tqleegvl