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dTDP-4-dehydrorhamnose reductase [Klebsiella pneumoniae subsp.


LOCUS       YP_005227856             296 aa            linear   CON 02-JUN-2020
            pneumoniae HS11286].
ACCESSION   YP_005227856
VERSION     YP_005227856.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 296)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 296)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 296)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW62254.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..296
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /calculated_mol_wt=32029
     Region          1..296
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(7,9..12,30..31,38..41,61..63,65,80,102..104,128,132,
                     151..154)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:187564"
     Site            order(81,104,128,132)
                     /site_type="active"
                     /db_xref="CDD:187564"
     Site            order(104,128,153,166,178,184)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:187564"
     CDS             1..296
                     /locus_tag="KPHS_35560"
                     /coded_by="complement(NC_016845.1:3557005..3557895)"
                     /transl_table=11
                     /db_xref="GeneID:11848587"
CONTIG      join(WP_004175259.1:1..296)
ORIGIN      
        1 mkilligkng qvgwelqrsl stlgdvvavd yfdkelcgdl tnldgiaqtv rtvrpdvvvn
       61 aaahtavdka eserelsdll ndkgvavlaa esaklgalmv hystdyvfdg agshyrrede
      121 atgplnvyge tkragelale qgnprhlifr tswvyatrga nfaktmlrla geketlsiid
      181 dqhgaptgae lladctatai retlrdpala gtyhlvasge tswcdyaryv fevarahgae
      241 lavqevkgip ttayptpakr plnsrlsnek fqqafgvtlp dwrqgvarvv tevlgk