MULTISPECIES: dTDP-4-dehydrorhamnose reductase

LOCUS       WP_004175259             296 aa            linear   BCT 31-MAY-2019
            [Enterobacteriaceae].
ACCESSION   WP_004175259
VERSION     WP_004175259.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007440.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09987
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..296
                     /gene="rfbD"
     Protein         1..296
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /EC_number="1.1.1.133"
                     /calculated_mol_wt=32029
     Region          1..296
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(7,9..12,30..31,38..41,61..63,65,80,102..104,128,132,
                     151..154)
                     /site_type="other"
                     /note="NADP binding site [chemical binding]"
                     /db_xref="CDD:187564"
     Site            order(81,104,128,132)
                     /site_type="active"
                     /db_xref="CDD:187564"
     Site            order(104,128,153,166,178,184)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:187564"
ORIGIN      
        1 mkilligkng qvgwelqrsl stlgdvvavd yfdkelcgdl tnldgiaqtv rtvrpdvvvn
       61 aaahtavdka eserelsdll ndkgvavlaa esaklgalmv hystdyvfdg agshyrrede
      121 atgplnvyge tkragelale qgnprhlifr tswvyatrga nfaktmlrla geketlsiid
      181 dqhgaptgae lladctatai retlrdpala gtyhlvasge tswcdyaryv fevarahgae
      241 lavqevkgip ttayptpakr plnsrlsnek fqqafgvtlp dwrqgvarvv tevlgk