L-Ala-D/L-Glu epimerase, a muconate lactonizing enzyme [Klebsiella

LOCUS       YP_005227145             387 aa            linear   CON 02-JUN-2020
            pneumoniae subsp. pneumoniae HS11286].
ACCESSION   YP_005227145
VERSION     YP_005227145.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 387)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 387)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 387)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW61543.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..387
                     /product="L-Ala-D/L-Glu epimerase, a muconate lactonizing
                     enzyme"
                     /calculated_mol_wt=40631
     Region          19..380
                     /region_name="MLE"
                     /note="Muconate Lactonizing Enzyme (MLE), an homooctameric
                     enzyme, catalyses the conversion of cis,cis-muconate (CCM)
                     to muconolactone (ML) in the catechol branch of the
                     beta-ketoadipate pathway. This pathway is used in soil
                     microbes to breakdown lignin-derived...; cd03318"
                     /db_xref="CDD:239434"
     Site            order(75,77,79,84,88,99..100,102,111..113,115,140,
                     143..145,244,270,302,332)
                     /site_type="other"
                     /note="octamer interface [polypeptide binding]"
                     /db_xref="CDD:239434"
     Site            order(181,183,212,214,238,263..264,287,340)
                     /site_type="active"
                     /db_xref="CDD:239434"
     CDS             1..387
                     /locus_tag="KPHS_28450"
                     /coded_by="complement(NC_016845.1:2844634..2845797)"
                     /transl_table=11
                     /db_xref="GeneID:11847863"
CONTIG      join(WP_014343109.1:1..387)
ORIGIN      
        1 mdvgtksyis hqeqkmtati eqieswivdv ptirphklsm ttmgcqslvi vrltrsdgic
       61 gigeattigg lsygvespea ilsaithylt pllkgqpadn lnaltarmng aikgntfaks
      121 aietalldaq gkalglpvsa llggalqtal pvlwtlasgd takdiaegek llaegrhraf
      181 klkigarela tdlrhtraiv ealgdrasir vdvnqawdaa tgakgcrela amgvdlieqp
      241 vsahdnaalv rfsqqietai ladeavatay dgyqlaqqgf tgayalkiak aggpnsvlal
      301 arvaqaagig lyggtmlegt vgtvaslhaw stlplqwgte mfgplllkdd ivsvpltfad
      361 gqvalpqtpg lgveldedkl hfytrqp