Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: muconate cycloisomerase family protein [Klebsiella].


LOCUS       WP_014343109             387 aa            linear   BCT 13-MAY-2021
ACCESSION   WP_014343109
VERSION     WP_014343109.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10129518
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..387
                     /product="muconate cycloisomerase family protein"
                     /calculated_mol_wt=40631
     Region          19..380
                     /region_name="MLE"
                     /note="Muconate Lactonizing Enzyme (MLE), an homooctameric
                     enzyme, catalyses the conversion of cis,cis-muconate (CCM)
                     to muconolactone (ML) in the catechol branch of the
                     beta-ketoadipate pathway. This pathway is used in soil
                     microbes to breakdown lignin-derived...; cd03318"
                     /db_xref="CDD:239434"
     Site            order(75,77,79,84,88,99..100,102,111..113,115,140,
                     143..145,244,270,302,332)
                     /site_type="other"
                     /note="octamer interface [polypeptide binding]"
                     /db_xref="CDD:239434"
     Site            order(181,183,212,214,238,263..264,287,340)
                     /site_type="active"
                     /db_xref="CDD:239434"
ORIGIN      
        1 mdvgtksyis hqeqkmtati eqieswivdv ptirphklsm ttmgcqslvi vrltrsdgic
       61 gigeattigg lsygvespea ilsaithylt pllkgqpadn lnaltarmng aikgntfaks
      121 aietalldaq gkalglpvsa llggalqtal pvlwtlasgd takdiaegek llaegrhraf
      181 klkigarela tdlrhtraiv ealgdrasir vdvnqawdaa tgakgcrela amgvdlieqp
      241 vsahdnaalv rfsqqietai ladeavatay dgyqlaqqgf tgayalkiak aggpnsvlal
      301 arvaqaagig lyggtmlegt vgtvaslhaw stlplqwgte mfgplllkdd ivsvpltfad
      361 gqvalpqtpg lgveldedkl hfytrqp