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putative voltage-gated ClC-type chloride channel ClcB [Klebsiella


LOCUS       YP_005226787             431 aa            linear   CON 02-JUN-2020
            pneumoniae subsp. pneumoniae HS11286].
ACCESSION   YP_005226787
VERSION     YP_005226787.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 431)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 431)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 431)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW61185.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..431
                     /product="putative voltage-gated ClC-type chloride channel
                     ClcB"
                     /calculated_mol_wt=45483
     Region          13..430
                     /region_name="PRK01610"
                     /note="putative voltage-gated ClC-type chloride channel
                     ClcB; Provisional"
                     /db_xref="CDD:234963"
     Site            order(96..100,131..135,333..337)
                     /site_type="active"
                     /note="Cl- selectivity filter [active]"
                     /db_xref="CDD:238233"
     Site            order(97,99,133..134,333..335)
                     /site_type="other"
                     /note="Cl- binding residues [ion binding]"
                     /db_xref="CDD:238233"
     Site            133
                     /site_type="active"
                     /note="pore gating glutamate residue [active]"
                     /db_xref="CDD:238233"
     Site            order(177,186,201,208,381,384,392,400,407..408)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238233"
     CDS             1..431
                     /locus_tag="KPHS_24870"
                     /coded_by="complement(NC_016845.1:2518124..2519419)"
                     /transl_table=11
                     /db_xref="GeneID:11847505"
CONTIG      join(WP_004148305.1:1..431)
ORIGIN      
        1 mhrlhpypdv qvmfrrllia tligllaala valfrhamvv letlllsnds gslvnaaqsl
       61 pawrrlvtpa lggltagtll wlwqrrsvar phaatdymea letgdgcfdt paslvkslas
      121 llvvvtgsai gregamilla alaaslfarr ftpqsewklw vacgaaagma sayhaplags
      181 lfiaeilfgt lmlaslgpvv isavialllt qflnggaapl yhvvlqqnls alhyglmlat
      241 gllaglcgpl fiwlmdyshr gfvklklapp wqlalggliv gglslitpav wgngysvvqs
      301 ylllppsgal lvgvfickll avlassgsga pggvftptlf vglamgmlfa cfsrlwlpgs
      361 eemaimmglt gmaaflaatt hapimstlmi cemtgqytll pgllitcvvs svlsrtlrrd
      421 siyrhhvaeh v