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delta-aminolevulinic acid dehydratase [Klebsiella pneumoniae subsp.


LOCUS       YP_005225354             324 aa            linear   CON 02-JUN-2020
            pneumoniae HS11286].
ACCESSION   YP_005225354
VERSION     YP_005225354.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 324)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 324)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 324)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW59752.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..324
                     /product="delta-aminolevulinic acid dehydratase"
                     /calculated_mol_wt=35325
     Region          4..319
                     /region_name="ALAD_PBGS"
                     /note="Porphobilinogen synthase (PBGS), which is also
                     called delta-aminolevulinic acid dehydratase (ALAD),
                     catalyzes the condensation of two 5-aminolevulinic acid
                     (ALA) molecules to form the pyrrole porphobilinogen (PBG),
                     which is the second step in the...; cl00338"
                     /db_xref="CDD:469728"
     Site            order(9,12..13,24,48,51,140..141,168..169,198..200,219,
                     222,228,231..232,250..254,278,296,300,303)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238226"
     Site            order(118,120,122,130,165,195,201,204..205,210,216,220,
                     247,270,273,312)
                     /site_type="active"
                     /db_xref="CDD:238226"
     Site            order(195,247)
                     /site_type="active"
                     /note="Schiff base residues [active]"
                     /db_xref="CDD:238226"
     CDS             1..324
                     /locus_tag="KPHS_10540"
                     /coded_by="complement(NC_016845.1:1113347..1114321)"
                     /transl_table=11
                     /db_xref="GeneID:11846052"
CONTIG      join(WP_002890201.1:1..324)
ORIGIN      
        1 mtdlitrprr lrqsaalral feettlslnd lvlpifveee iddykaieam pgvmripeky
       61 lareierian agirsvmtfg ishhtdatgs dtwnenglva rmsrickstv pemivmsdtc
      121 fceytshghc gvlcdhgvdn datlenlgkq avvaaaagad fiapsaamdg qvqairrsld
      181 aagftntaim systkfassf ygpfreaagt alkgdrktyq mspmnrreai reslldeaqg
      241 adclmvkpag ayldilrdir ersdlplgay qvsgeyamik faaqagaide ekvvleslga
      301 ikragadlif syfaldlaek kilr