H(+)/Cl(-) exchange transporter ClcA [Klebsiella pneumoniae subsp.

LOCUS       YP_005225204             503 aa            linear   CON 02-JUN-2020
            pneumoniae HS11286].
ACCESSION   YP_005225204
VERSION     YP_005225204.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 503)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 503)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 503)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW59602.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..503
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /calculated_mol_wt=53669
     Region          67..484
                     /region_name="PRK05277"
                     /note="H(+)/Cl(-) exchange transporter ClcA"
                     /db_xref="CDD:235385"
     Site            order(137..141,177..181,386..390,476)
                     /site_type="active"
                     /note="Cl- selectivity filter [active]"
                     /db_xref="CDD:238504"
     Site            order(138,140,179..180,386..388,476)
                     /site_type="other"
                     /note="Cl- binding residues [ion binding]"
                     /db_xref="CDD:238504"
     Site            179
                     /site_type="active"
                     /note="pore gating glutamate residue [active]"
                     /db_xref="CDD:238504"
     Site            order(225,234,247,254,434,437,445,457,464..465,468)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238504"
     Site            234
                     /site_type="active"
                     /note="H+/Cl- coupling transport residue [active]"
                     /db_xref="CDD:238504"
     CDS             1..503
                     /locus_tag="KPHS_09040"
                     /coded_by="NC_016845.1:954381..955892"
                     /transl_table=11
                     /db_xref="GeneID:11845894"
CONTIG      join(WP_004217649.1:1..503)
ORIGIN      
        1 mcrkgifltt qragaakmpl ssfvlpiidn gmkaetpsfe ahqfvrvrrg davrrliqrd
       61 ktplavlfma avvgtlaglv gvafeksvnw vqnqrigala qvadhwylvw plafilsall
      121 amvgyflvrr fapeaggsgi peiegaleel rpvrwwrvlp vkfvggmgtl gagmvlgreg
      181 pmvqlggnig rmvldvfrmr spearhtlla tgaasglsaa fnaplagilf iieemrpqfr
      241 ynlisikavf tgvimssivf rifngeaaii evgklsnapv ntlwlylvlg mlfgcfgplf
      301 nflvlrtqdl fqrihggnik kwvligglig glcgllglmq psavgggfnl ipiaaagnfs
      361 vglllfifia rvvttlicfs sgapggifap mlalgtllgt afgmaaiplf payhldagtf
      421 aiagmgalla asvrapltgi vlvlemtdny qlilpmiitc lgatllaqfl ggkplystil
      481 qrtlakqeae qaakaqqapr ent