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4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Klebsiella


LOCUS       YP_005225034             316 aa            linear   CON 02-JUN-2020
            pneumoniae subsp. pneumoniae HS11286].
ACCESSION   YP_005225034
VERSION     YP_005225034.1
DBLINK      BioProject: PRJNA84387
            Assembly: GCF_000240185.1
DBSOURCE    REFSEQ: accession NC_016845.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae subsp. pneumoniae HS11286
  ORGANISM  Klebsiella pneumoniae subsp. pneumoniae HS11286
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 316)
  AUTHORS   Liu,P., Li,P., Jiang,X., Bi,D., Xie,Y., Tai,C., Deng,Z.,
            Rajakumar,K. and Ou,H.Y.
  TITLE     Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
            HS11286, a multidrug-resistant strain isolated from human sputum
  JOURNAL   J. Bacteriol. 194 (7), 1841-1842 (2012)
   PUBMED   22408243
REFERENCE   2  (residues 1 to 316)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2012) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (residues 1 to 316)
  AUTHORS   Ou,H.-Y., Jiang,X., Liu,P. and Li,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2011) State Key Laboratory of Microbial
            Metabolism, Shanghai Jiaotong University, 1954 Huashan Road,
            Shanghai 200030, China
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AEW59432.
            RefSeq Category: Reference Genome
                        CLI: Clinical Isolate
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Klebsiella pneumoniae subsp. pneumoniae
                     HS11286"
                     /strain="HS11286"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:1125630"
     Protein         1..316
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /calculated_mol_wt=34316
     Region          1..301
                     /region_name="ispH"
                     /note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
                     Reviewed; PRK01045"
                     /db_xref="CDD:234893"
     Site            order(12,96,197)
                     /site_type="other"
                     /note="Fe-S cluster binding site [ion binding]"
                     /db_xref="CDD:260116"
     Site            order(15,40..41,73..74,124,126,167..168,224..227,269)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:260116"
     Site            order(124,126,225,227)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:260116"
     CDS             1..316
                     /locus_tag="KPHS_07340"
                     /coded_by="NC_016845.1:773735..774685"
                     /transl_table=11
                     /db_xref="GeneID:11845724"
CONTIG      join(WP_002887979.1:1..316)
ORIGIN      
        1 mqillanprg fcagvdrais ivenaltlyg apiyvrhevv hnryvvdslr krgaifieqi
       61 sevpdgaili fsahgvsqav rneaksrdlt vfdatcplvt kvhmevaras rrgeesilig
      121 haghpevegt mgqynnpqgg mylvespedv lklevkndar lsfmtqttls vddtsdvida
      181 lrarfpkivg prkddicyat tnrqeavral aeqadvvlvv gsknssnsnr laelaqrmgk
      241 aayliddasd iqeawvkdaa cvgvtagasa pdilvqnvit rlqelgggea vplegreeni
      301 vfevpkelrv dvreve