Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

tethering complex subunit [Candida albicans SC5314].


LOCUS       XP_719146                810 aa            linear   PLN 18-APR-2022
ACCESSION   XP_719146
VERSION     XP_719146.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_714053.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 810)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 810)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 810)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 810)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 810)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 810)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30233.
            
            On Dec 8, 2016 this sequence version replaced XP_719146.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..810
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..810
                     /product="tethering complex subunit"
                     /calculated_mol_wt=94110
     Region          <255..363
                     /region_name="Pep3_Vps18"
                     /note="Pep3/Vps18/deep orange family; pfam05131"
                     /db_xref="CDD:461557"
     Region          533..684
                     /region_name="Clathrin"
                     /note="Region in Clathrin and VPS; pfam00637"
                     /db_xref="CDD:459884"
     Region          767..804
                     /region_name="RING_Ubox"
                     /note="RING finger (Really Interesting New Gene) domain
                     and U-box domain superfamily; cl17238"
                     /db_xref="CDD:473075"
     Site            order(769,772,787,789,792,795,801,804)
                     /site_type="other"
                     /note="cross-brace motif"
                     /db_xref="CDD:438111"
     CDS             1..810
                     /gene="PEP3"
                     /locus_tag="CAALFM_C603020WA"
                     /coded_by="XM_714053.2:1..2433"
                     /note="Peptidase; activity useful for strain
                     identification by multilocus enzyme electrophoresis
                     (MLEE); clade-associated gene expression"
                     /transl_table=12
                     /db_xref="CGD:CAL0000182547"
                     /db_xref="GeneID:3639267"
ORIGIN      
        1 mssnghktks iksetnssyt vhsldqqqas icdnlqqakf elepvhlqfs lsnklnkllv
       61 ssnimyillx nvvykidldn psqvenyalp gkvtnawlnp ngqtlivqie kqayytlekk
      121 vfkllkfkni evtsiafsnh nmvvgtkdgi iyvyekslkq vykvdspvqg vmfsndysqi
      181 nvlanslytw dcfdtsyvel qkvfkqttpv iksinppgif tsnpqnyvyi ssdneiitnd
      241 eemqldrvde efsqialtph hligiegnsl kiynklnkql qelslsenki rgiavdnlfn
      301 tywvytknsi yefvienesi svwydyykmg kysealkyld eddeanfskr dlvlikqgyd
      361 ylqrggfgis sddlslqiqg iqilakstep fekvclmlln hkqsdallie yllaklnkkn
      421 kvrxivlsaw iielmvrndd srvyefiktn yklldrptmy qilnseklif yaeliedynf
      481 ilkyyidkkn wtlavktlik lytkgdielv yenatillmn ypkvtetwlk ldleyekllp
      541 allkhqeqai hflqqvimdk hykknkqlnn aylcllitkp gtdkqiikfi nftsnfdtnf
      601 ilrlcishek fhpavliyie iglfdqalel alkhdltsla efilnkyded kqvegikled
      661 anynvkrklw lkfakylidk sddlnetlhh ivnvsmldlk dllplfpeti sinnfkdeiv
      721 eslneynkri vhlsldmnns sehlremkkk viynkkktnv aiiepgepcr kcgkllvqen
      781 fvyfpnchha fhkecmkknq cllcndflnl