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Rnh1p [Candida albicans SC5314].


LOCUS       XP_719125                233 aa            linear   PLN 18-APR-2022
ACCESSION   XP_719125
VERSION     XP_719125.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_714032.1
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 233)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 233)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 233)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 233)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 233)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 233)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30218.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..233
                     /product="Rnh1p"
                     /calculated_mol_wt=26632
     Region          2..45
                     /region_name="Cauli_VI"
                     /note="Caulimovirus viroplasmin; pfam01693"
                     /db_xref="CDD:460297"
     Region          57..218
                     /region_name="RNase_HI_eukaryote_like"
                     /note="Eukaryotic RNase H is essential and is longer and
                     more complex than their prokaryotic counterparts; cd09280"
                     /db_xref="CDD:260012"
     Site            order(60..63,65..67,102..104,107,136,138..139,165..166,
                     196,199,214)
                     /site_type="other"
                     /note="RNA/DNA hybrid binding site [nucleotide binding]"
                     /db_xref="CDD:260012"
     CDS             1..233
                     /gene="RNH1"
                     /locus_tag="CAALFM_C602870WA"
                     /coded_by="XM_714032.1:1..702"
                     /note="Ribonuclease H (RNAse H); hyphal-induced;
                     flucytosine induced; similar to orf19.5564 (see Locus
                     History); possibly essential (UAU1 method); rat catheter
                     biofilm induced; flow model biofilm repressed"
                     /transl_table=12
                     /db_xref="CGD:CAL0000191701"
                     /db_xref="GeneID:3639237"
ORIGIN      
        1 mpyyavvngr eegvfsswqd crphvfaykg ahfrkfenrn eaeeyyqndg dyfiypiyvd
       61 gacryngcph aeagygvyyg dgdsrnvsvp lddvdpdgii ptnqraelwa mnhalrniwn
      121 elqedtedgk aviysdsiya ikcltkwpnk wtqngwlnvh gqtisnydlv tknyelyewi
      181 ndeyddrgwg eldlihvkgh sgndgneead nlanlaadry gyqssssssg syy