NADPH dehydrogenase [Candida albicans SC5314].

LOCUS       XP_716750                403 aa            linear   PLN 18-APR-2022
ACCESSION   XP_716750
VERSION     XP_716750.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_711657.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 403)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 403)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 403)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 403)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 403)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30082.
            
            On Dec 8, 2016 this sequence version replaced XP_716750.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..403
                     /product="NADPH dehydrogenase"
                     /calculated_mol_wt=45637
     Region          17..366
                     /region_name="OYE_like_FMN"
                     /note="Old yellow enzyme (OYE)-like FMN binding domain.
                     OYE was the first flavin-dependent enzyme identified,
                     however its true physiological role remains elusive to
                     this day. Each monomer of OYE contains FMN as a
                     non-covalently bound cofactor, uses NADPH as a...;
                     cd02933"
                     /db_xref="CDD:239243"
     Site            order(37,39,72,114,244,319,340,342..344)
                     /site_type="other"
                     /note="FMN binding site [chemical binding]"
                     /db_xref="CDD:239243"
     Site            order(37,39,72,114,116,123,191,194,196,244,251,319,340,
                     342..343)
                     /site_type="active"
                     /db_xref="CDD:239243"
     Site            order(39,116,191,194,196,343)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:239243"
     Site            196
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:239243"
     CDS             1..403
                     /gene="OYE2"
                     /locus_tag="CAALFM_C601410CA"
                     /coded_by="XM_711657.2:1..1212"
                     /note="Putative NAPDH dehydrogenase; induced by nitric
                     oxide; Spider biofilm induced"
                     /transl_table=12
                     /db_xref="CGD:CAL0000196620"
                     /db_xref="GeneID:3641603"
ORIGIN      
        1 mtidnegivi kplgstklfq piklgsntls qriafapstr yratkdnipt dlqleyysqr
       61 seypgtliit eatytsrqgg lvpyvpgiyn daqtkswkki ndaihangsf ssvqlwylgr
      121 vanpknlkda glpfvgassv ywneesekla keagnelrel teeeidhive veypnaakra
      181 ieagfdyiev hsahgylldq flnlasnkrt dkygcgsien rarlllriid klidivgaer
      241 lavrlspwat fqnvdvegee ihsyiidqlq eransgnela yislveprvq aswdiakenq
      301 vgsnefilkh wkgkviragt yahelnkine dinndrtlia fsrffisnpd lvkklhdgis
      361 ltpyeratfy nhdnfgyntw ikygenkvfn eqeerkklgk pla