putative pyridoxal kinase [Candida albicans SC5314].

LOCUS       XP_716720                295 aa            linear   PLN 18-APR-2022
ACCESSION   XP_716720
VERSION     XP_716720.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_711627.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 295)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 295)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 295)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 295)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 295)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 295)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30112.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..295
                     /product="putative pyridoxal kinase"
                     /calculated_mol_wt=33017
     Region          3..257
                     /region_name="pyridoxal_pyridoxamine_kinase"
                     /note="Pyridoxal kinase plays a key role in the synthesis
                     of the active coenzyme pyridoxal-5'-phosphate (PLP), by
                     catalyzing the phosphorylation of the precursor vitamin B6
                     in the presence of Zn2+ and ATP. Mammals are unable to
                     synthesize PLP de novo and...; cd01173"
                     /db_xref="CDD:238578"
     Site            order(3,10,12..13,15,19,23,26,31..36,39,42,51..52,54,
                     61..62,69)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238578"
     Site            order(9,16..17,40,43..44,49,83,85,215..216,219)
                     /site_type="other"
                     /note="pyridoxal binding site [chemical binding]"
                     /db_xref="CDD:238578"
     Site            order(113,118,145,147,150,184..185,192,207,209..210,214,
                     217..219,221,248,252)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:238578"
     CDS             1..295
                     /locus_tag="CAALFM_C601750CA"
                     /coded_by="XM_711627.2:1..888"
                     /note="Ortholog(s) have role in cellular bud site
                     selection and cytosol, nucleus localization"
                     /transl_table=12
                     /db_xref="CGD:CAL0000178296"
                     /db_xref="GeneID:3641640"
ORIGIN      
        1 mksllsissh vvhgyvgnra tvfplqyagw dvdainttnf snhpgygsls gtasppeaiq
       61 diilglkqil dfnnvydiil tgytpnaevl qilkseieqa itnsrnkphw ivdpvlgdng
      121 klyvkenlip vyrdifasgl velttpnqfe fetlsgvkiv dwstakdaiy efrklykvkn
      181 ivissvsidd hlycvgssnd rifyisieqi gcsfngcgdl ftalladefy ngeyvlspqm
      241 lskvlyklhk ilefsyddif krigqiptvv kdirvvaake fltsdykldt dviyl