Plb1p [Candida albicans SC5314].

LOCUS       XP_713822                605 aa            linear   PLN 18-APR-2022
ACCESSION   XP_713822
VERSION     XP_713822.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_708729.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 605)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 605)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 605)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 605)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 605)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 605)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30135.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..605
                     /product="Plb1p"
                     /calculated_mol_wt=66286
     Region          26..568
                     /region_name="cPLA2_Fungal_PLB"
                     /note="Fungal Phospholipase B-like; cPLA2 GrpIVA homologs;
                     catalytic domain; cd07203"
                     /db_xref="CDD:132842"
     Site            order(95..96,98,135,382)
                     /site_type="active"
                     /db_xref="CDD:132842"
     Site            133..137
                     /site_type="other"
                     /note="nucleophile elbow"
                     /db_xref="CDD:132842"
     Site            order(325,355)
                     /site_type="other"
                     /note="flexible lid region"
                     /db_xref="CDD:132842"
     CDS             1..605
                     /gene="PLB1"
                     /locus_tag="CAALFM_C601990WA"
                     /coded_by="XM_708729.2:1..1818"
                     /note="Phospholipase B; host cell penetration and
                     virulence in mouse systemic infection; Hog1-induced;
                     signal sequence, N-glycosylation, and Tyr phosphorylation
                     site; induced in fluconazole-resistant strains; rat
                     catheter biofilm repressed"
                     /transl_table=12
                     /db_xref="CGD:CAL0000177213"
                     /db_xref="GeneID:3644561"
ORIGIN      
        1 milhhllill iinycvatsp tngyapgpvs cpssqlirsg sqginpneqs yinarypiak
       61 qalskflhna nlqnfdvdsf lahsnptigl afsgggyram ltgageissl dsrtktntpv
      121 lagilqassy iaglsggswl vgslasnnln svddmlsqgl welthsflsy ygiehpikqv
      181 eewvnvgnqv askrnanfnv sltdiygrll syplltnted egdaylwsdv tsasnfqshq
      241 mpfpilisdg rapdttiinl nstvieltpy efgswdpsln efvdtrylgt kldngrptgk
      301 cyngfdnagf fmgtssalfn eavlsitean ipsflkdiid dilvdpilks nidvsaynpn
      361 pffkssgsnt aisqsknlyl vdggedgqni pispllhrnv saifafdnsn dvlnwpdgts
      421 lvktyerqfs sqgngiafpy vpdqytfrnl nltskptffg cdaknltslt kdiydvplvi
      481 ylanrpftyw sntstfklty ddnerqgmis ngfeiatrss gslddewaac vgcaiirreq
      541 erqgieqteq ckrcfenycw dgtiykgepl genfsddglt nsateynsnn vagfndggts
      601 ilkka