Candida albicans SC5314 Plb1p (PLB1), partial mRNA.

LOCUS       XM_708729               1818 bp    mRNA    linear   PLN 18-APR-2022
ACCESSION   XM_708729
VERSION     XM_708729.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (bases 1 to 1818)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (bases 1 to 1818)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (bases 1 to 1818)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (bases 1 to 1818)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 1818)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (bases 1 to 1818)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NC_032094).
            
            On Dec 8, 2016 this sequence version replaced XM_708729.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1818
                     /organism="Candida albicans SC5314"
                     /mol_type="mRNA"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     gene            <1..>1818
                     /gene="PLB1"
                     /locus_tag="CAALFM_C601990WA"
                     /db_xref="GeneID:3644561"
     CDS             1..1818
                     /gene="PLB1"
                     /locus_tag="CAALFM_C601990WA"
                     /note="Phospholipase B; host cell penetration and
                     virulence in mouse systemic infection; Hog1-induced;
                     signal sequence, N-glycosylation, and Tyr phosphorylation
                     site; induced in fluconazole-resistant strains; rat
                     catheter biofilm repressed"
                     /codon_start=1
                     /transl_table=12
                     /product="Plb1p"
                     /protein_id="XP_713822.1"
                     /db_xref="CGD:CAL0000177213"
                     /db_xref="GeneID:3644561"
                     /translation="MILHHLLILLIINYCVATSPTNGYAPGPVSCPSSQLIRSGSQGI
                     NPNEQSYINARYPIAKQALSKFLHNANLQNFDVDSFLAHSNPTIGLAFSGGGYRAMLT
                     GAGEISSLDSRTKTNTPVLAGILQASSYIAGLSGGSWLVGSLASNNLNSVDDMLSQGL
                     WELTHSFLSYYGIEHPIKQVEEWVNVGNQVASKRNANFNVSLTDIYGRLLSYPLLTNT
                     EDEGDAYLWSDVTSASNFQSHQMPFPILISDGRAPDTTIINLNSTVIELTPYEFGSWD
                     PSLNEFVDTRYLGTKLDNGRPTGKCYNGFDNAGFFMGTSSALFNEAVLSITEANIPSF
                     LKDIIDDILVDPILKSNIDVSAYNPNPFFKSSGSNTAISQSKNLYLVDGGEDGQNIPI
                     SPLLHRNVSAIFAFDNSNDVLNWPDGTSLVKTYERQFSSQGNGIAFPYVPDQYTFRNL
                     NLTSKPTFFGCDAKNLTSLTKDIYDVPLVIYLANRPFTYWSNTSTFKLTYDDNERQGM
                     ISNGFEIATRSSGSLDDEWAACVGCAIIRREQERQGIEQTEQCKRCFENYCWDGTIYK
                     GEPLGENFSDDGLTNSATEYNSNNVAGFNDGGTSILKKA"
     misc_feature    76..1704
                     /gene="PLB1"
                     /locus_tag="CAALFM_C601990WA"
                     /note="Fungal Phospholipase B-like; cPLA2 GrpIVA homologs;
                     catalytic domain; Region: cPLA2_Fungal_PLB; cd07203"
                     /db_xref="CDD:132842"
     misc_feature    order(283..288,292..294,403..405,1144..1146)
                     /gene="PLB1"
                     /locus_tag="CAALFM_C601990WA"
                     /note="active site"
                     /db_xref="CDD:132842"
     misc_feature    397..411
                     /gene="PLB1"
                     /locus_tag="CAALFM_C601990WA"
                     /note="nucleophile elbow; other site"
                     /db_xref="CDD:132842"
     misc_feature    order(973..975,1063..1065)
                     /gene="PLB1"
                     /locus_tag="CAALFM_C601990WA"
                     /note="flexible lid region; other site"
                     /db_xref="CDD:132842"
ORIGIN      
        1 atgattttgc atcatttgtt aattttgctt attataaatt attgtgttgc tacatcacca
       61 actaatggat atgctcctgg tccggtttct tgcccaagca gtcaattgat tagatctgga
      121 tctcagggga tcaatccaaa tgaacaatca tatatcaatg ccagatatcc tattgccaaa
      181 caagcattgt ctaagttttt acacaatgca aacttacaaa actttgatgt tgattcgttc
      241 ttagcacact ccaatccaac tattggtctt gcattcagtg gcggagggta tagagcaatg
      301 ttgactggag caggtgaaat cagtagcttg gactcaagaa caaaaaccaa tactccagtt
      361 ttagcaggca ttttacaagc ttcgagttat attgctgggt tatcaggtgg atcgtggtta
      421 gttggaagtc ttgcaagtaa taatttgaac tctgttgatg acatgttatc tcaaggtttg
      481 tgggaactca cacactcatt tcttagttac tatggcattg aacatcctat aaagcaagtt
      541 gaagaatggg ttaatgttgg taatcaagtt gccagcaaaa gaaatgcaaa ttttaacgtt
      601 tctttaactg acatatatgg aagactatta agttaccctt tgctcacaaa cacagaagac
      661 gaaggtgatg cttatttgtg gtcagatgta acgagtgctt caaacttcca aagccaccaa
      721 atgccgtttc caatattgat cagtgatggt agagctccag atactaccat tattaatctc
      781 aactccactg tgattgaatt aactccatac gaatttggtt catgggatcc tagtttaaat
      841 gaatttgttg acactagata tttgggaaca aaattagaca atggtcgtcc aactggtaag
      901 tgttataatg gatttgacaa tgctgggttt ttcatgggta cttcttctgc tcttttcaac
      961 gaagcggtgt tgtctatcac tgaagctaac atacctagct ttttaaaaga tataattgat
     1021 gatattttgg tagatccaat tctcaagtcc aacatagacg tgtctgctta caatccaaat
     1081 ccatttttca aaagttctgg cagcaatact gctatttctc aatcaaaaaa tctttattta
     1141 gttgacggtg gagaagatgg ccaaaacatt ccaataagtc ccttgttgca tcgtaacgta
     1201 agtgctatat ttgcctttga caattccaat gacgttttaa actggccaga tgggacttcg
     1261 ttggtgaaaa cttatgaacg tcaattctca tcacagggta atggtattgc tttcccatat
     1321 gttcctgatc aatacacttt ccgtaatttg aacttgacta gcaaacctac attttttggt
     1381 tgcgatgcaa aaaacttgac ttcattgaca aaggatattt atgatgttcc cttggttata
     1441 tacttggcaa atcgtccatt cacttactgg tctaatacat caactttcaa attaacatac
     1501 gacgataacg aaagacaagg catgatttcc aatggatttg aaattgccac tagatcaagt
     1561 ggatccttgg atgatgaatg ggcagcatgt gttggatgcg ccatcatacg gagagagcaa
     1621 gaaagacaag gtattgaaca gacagaacaa tgtaagagat gctttgaaaa ctattgctgg
     1681 gatggtacca tctataaggg tgagccatta ggtgaaaact ttagtgatga tggattaact
     1741 aatagtgcta ccgaatataa cctgaataat gtagctgggt ttaatgacgg aggaactctg
     1801 attttgaaaa aggcataa