Nag4p [Candida albicans SC5314].

LOCUS       XP_712435                581 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712435
VERSION     XP_712435.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707342.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 581)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 581)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 581)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 581)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 581)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 581)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30378.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..581
                     /product="Nag4p"
                     /calculated_mol_wt=64461
     Region          135..567
                     /region_name="MFS_Tpo1_MDR_like"
                     /note="Yeast Polyamine transporter 1 (Tpo1) and similar
                     multidrug resistance (MDR) transporters of the Major
                     Facilitator Superfamily; cd17323"
                     /db_xref="CDD:340881"
     Site            order(145..146,149..150,153,186,236..237,239..241,244,264,
                     267..268,271,373,376..377,380..382,385,409,413,487..488,
                     492,496,511,514..515,518..519,522)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340881"
     CDS             1..581
                     /gene="NAG4"
                     /locus_tag="CAALFM_C604620CA"
                     /coded_by="XM_707342.2:1..1746"
                     /note="Putative transporter; fungal-specific; similar to
                     Nag3p and to S. cerevisiae Ypr156Cp and Ygr138Cp; required
                     for wild-type mouse virulence and wild-type cycloheximide
                     resistance; gene cluster encodes enzymes of GlcNAc
                     catabolism"
                     /transl_table=12
                     /db_xref="CGD:CAL0000197244"
                     /db_xref="GeneID:3645978"
ORIGIN      
        1 mshatdstld nasvdsekvr dfgddlqnhp vqptrsilsk irsrdddars lvsnnkgver
       61 iisdlqegag qlgpleqpyd ikkiethpdp htdyneadpw kypidsesgl rlvewvdgdk
      121 hnpkniskak kwlytlvlga vcfvvalgsa ivtgdmerpa eyfgvseevi ilasvtvfvi
      181 gfgvgplvfa pmseevgrkp iyvvtlfiav vfivpcgaak niatlivcrl idgiafsapm
      241 tliggsladi wegpergtam aifsaapflg pvcgpifggl lcdhaptwrw iywtflivag
      301 vfyaifiaiv pethhgillk krakklrket gdsryrsfne lqirsfgeva ktsllrpfvl
      361 lselivflmt iymaicygll ymfffaypvv yqqgkgwsas ltgvmfipig vgviiatiaa
      421 pffnkdynrr aqvyrdrgel pppelrlipm miacwfvpvg lfafawssyt wvswagpcfs
      481 glaagfgfcc lynpannyiv dsyqhyaasa laaktfvrsi wgacvplfti qmyhrlgdqw
      541 atslmafisl accaipylff ffgarvrtfs ryaytpetnt k