Nag3p [Candida albicans SC5314].

LOCUS       XP_712434                561 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712434
VERSION     XP_712434.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707341.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 561)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 561)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 561)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 561)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 561)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 561)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30377.
            
            On Dec 8, 2016 this sequence version replaced XP_712434.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..561
                     /product="Nag3p"
                     /calculated_mol_wt=62473
     Region          117..549
                     /region_name="MFS_Tpo1_MDR_like"
                     /note="Yeast Polyamine transporter 1 (Tpo1) and similar
                     multidrug resistance (MDR) transporters of the Major
                     Facilitator Superfamily; cd17323"
                     /db_xref="CDD:340881"
     Site            order(127..128,131..132,135,168,218..219,221..223,226,246,
                     249..250,253,355,358..359,362..364,367,391,395,469..470,
                     474,478,493,496..497,500..501,504)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340881"
     CDS             1..561
                     /gene="NAG3"
                     /locus_tag="CAALFM_C604610CA"
                     /coded_by="XM_707341.2:1..1686"
                     /note="Putative MFS transporter; similar to Nag4; required
                     for wild-type mouse virulence and cycloheximide
                     resistance; in gene cluster that includes genes encoding
                     enzymes of GlcNAc catabolism; Spider biofilm repressed"
                     /transl_table=12
                     /db_xref="CGD:CAL0000181510"
                     /db_xref="GeneID:3645969"
ORIGIN      
        1 msdnttldni svnsekvvdy tihhddrkel erlvshnkgv ekivselaeg agqlgpleqp
       61 ydihkvethp dphtdyndad pwkypidket klrlvdwteg dkhnpknfgk gfkwlctvll
      121 gmicfvvalg saivtgdler paadfgvsee viilasvtmf vigfgvgplv fapmseevgr
      181 kpiyvvtlfv avvfivpcga aqniatllic rlidgtafsa pmtliggsla diwegpergt
      241 amavfsaapf lgpvcgpifg gllcdyaptw rwvywtfliv agffyvvfiv vvpethhgil
      301 lkkrakklrk dtgdsryrsf nelqirtfaq vaktsllrpf vllselivfl vtmymsvlyg
      361 llymfffayp ivyqegkgws asktgvmfip igvgviassl aapffnkdyn rraqeyrdrg
      421 elppaelrli pmmigcwfvp aglfafawss yqrlswagpc fsgfavgfgf lllynpanny
      481 ivdsyqhyaa salaaktfvr siwgacvplf tiqmyhrlgd ewatslmafi slaccaipyl
      541 fyifgarirt fskyayapnm d