Dac1p [Candida albicans SC5314].

LOCUS       XP_712432                413 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712432
VERSION     XP_712432.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707339.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 413)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 413)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 413)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 413)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 413)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 413)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30376.
            
            On Dec 8, 2016 this sequence version replaced XP_712432.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..413
                     /product="Dac1p"
                     /calculated_mol_wt=45095
     Region          4..392
                     /region_name="NagA"
                     /note="N-acetylglucosamine-6-phosphate deacetylase, NagA,
                     catalyzes the hydrolysis of the N-acetyl group of
                     N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to
                     glucosamine 6-phosphate and acetate. This is the first
                     committed step in the biosynthetic pathway to...; cd00854"
                     /db_xref="CDD:238434"
     Site            order(61,63,140,151,208,229,232..233,266,288,322)
                     /site_type="active"
                     /db_xref="CDD:238434"
     Site            order(231,237,239..240,242,249..250,265..268,270..271,
                     273..274,277)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238434"
     CDS             1..413
                     /gene="DAC1"
                     /locus_tag="CAALFM_C604600WA"
                     /coded_by="XM_707339.2:1..1242"
                     /note="N-acetylglucosamine-6-phosphate (GlcNAcP)
                     deacetylase; N-acetylglucosamine utilization; required for
                     wild-type hyphal growth and virulence in mouse systemic
                     infection; gene and protein are GlcNAc-induced; Spider
                     biofilm induced"
                     /transl_table=12
                     /db_xref="CGD:CAL0000190825"
                     /db_xref="GeneID:3645967"
ORIGIN      
        1 msftrftnch lidngelyef tdlyvnnatk richppanpe lvsevidlkq qilapgfidi
       61 qnngiyglnf snlgeestae dvaefkrfyr damakylstg vtatcptvts sfpevyakvl
      121 pmykrsvlas qtdslgahve gpfinvqkkg chpvetfvda kegeskllev ygdlfdnvci
      181 vtaapeiagv ldlipvvksk ncvfsightm sdydtavkav ekgatmithl ynampqphhr
      241 nagvvglins pivdtpyfgl icdgvhvdps mvnlayrsnp skcvlvtdam hliglpdghy
      301 kwdsqvivkt gdrlylentd tlagaattlp qcvrnlvkws qislpqavmt vtnnaaksig
      361 vdhergflnv gcladfvvld ksgfvrkvyk lgrevqssdi pldratdklt avl