Candida albicans SC5314 Dac1p (DAC1), partial mRNA.

LOCUS       XM_707339               1242 bp    mRNA    linear   PLN 18-APR-2022
ACCESSION   XM_707339
VERSION     XM_707339.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (bases 1 to 1242)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (bases 1 to 1242)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (bases 1 to 1242)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 1242)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (bases 1 to 1242)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NC_032094).
            
            On Dec 8, 2016 this sequence version replaced XM_707339.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Candida albicans SC5314"
                     /mol_type="mRNA"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     gene            <1..>1242
                     /gene="DAC1"
                     /locus_tag="CAALFM_C604600WA"
                     /db_xref="GeneID:3645967"
     CDS             1..1242
                     /gene="DAC1"
                     /locus_tag="CAALFM_C604600WA"
                     /note="N-acetylglucosamine-6-phosphate (GlcNAcP)
                     deacetylase; N-acetylglucosamine utilization; required for
                     wild-type hyphal growth and virulence in mouse systemic
                     infection; gene and protein are GlcNAc-induced; Spider
                     biofilm induced"
                     /codon_start=1
                     /transl_table=12
                     /product="Dac1p"
                     /protein_id="XP_712432.2"
                     /db_xref="CGD:CAL0000190825"
                     /db_xref="GeneID:3645967"
                     /translation="MSFTRFTNCHLIDNGELYEFTDLYVNNATKRICHPPANPELVSE
                     VIDLKQQILAPGFIDIQNNGIYGLNFSNLGEESTAEDVAEFKRFYRDAMAKYLSTGVT
                     ATCPTVTSSFPEVYAKVLPMYKRSVLASQTDSLGAHVEGPFINVQKKGCHPVETFVDA
                     KEGESKLLEVYGDLFDNVCIVTAAPEIAGVLDLIPVVKSKNCVFSIGHTMSDYDTAVK
                     AVEKGATMITHLYNAMPQPHHRNAGVVGLINSPIVDTPYFGLICDGVHVDPSMVNLAY
                     RSNPSKCVLVTDAMHLIGLPDGHYKWDSQVIVKTGDRLYLENTDTLAGAATTLPQCVR
                     NLVKWSQISLPQAVMTVTNNAAKSIGVDHERGFLNVGCLADFVVLDKSGFVRKVYKLG
                     REVQSSDIPLDRATDKLTAVL"
     misc_feature    10..1176
                     /gene="DAC1"
                     /locus_tag="CAALFM_C604600WA"
                     /note="N-acetylglucosamine-6-phosphate deacetylase, NagA,
                     catalyzes the hydrolysis of the N-acetyl group of
                     N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to
                     glucosamine 6-phosphate and acetate. This is the first
                     committed step in the biosynthetic pathway to...; Region:
                     NagA; cd00854"
                     /db_xref="CDD:238434"
     misc_feature    order(181..183,187..189,418..420,451..453,622..624,
                     685..687,694..699,796..798,862..864,964..966)
                     /gene="DAC1"
                     /locus_tag="CAALFM_C604600WA"
                     /note="active site"
                     /db_xref="CDD:238434"
     misc_feature    order(691..693,709..711,715..720,724..726,745..750,
                     793..804,808..813,817..822,829..831)
                     /gene="DAC1"
                     /locus_tag="CAALFM_C604600WA"
                     /note="dimer interface [polypeptide binding]; other site"
                     /db_xref="CDD:238434"
ORIGIN      
        1 atgtcattta ctagattcac aaactgtcat ttgatcgaca acggtgagtt gtatgagttt
       61 actgacttgt acgtcaacaa cgccaccaaa agaatttgtc atccgccagc aaaccctgag
      121 ttggttagtg aggttataga tttgaagcag caaatattag cacctgggtt tattgatatt
      181 cagaataacg gtatttatgg gttgaacttt tccaatcttg gcgaggagtc taccgcagag
      241 gatgttgctg agtttaagcg gttctataga gatgctatgg ccaagtattt gagtactggg
      301 gttactgcta cgtgtcctac tgtcacatca agcttcccag aagtgtatgc caaagtgttg
      361 ccaatgtaca agaggagtgt tttggcaagt cagacagatt cgcttggagc tcatgttgag
      421 gggccattta tcaatgtgca aaagaaaggg tgccacccag tcgaaacgtt tgttgatgcc
      481 aaagagggtg aatcaaaatt gttagaagtt tacggggact tgtttgataa tgtgtgtatt
      541 gtcactgctg ctcctgaaat tgctggtgtt ttagacttga tacctgttgt taaatccaag
      601 aactgtgtgt tttccattgg ccatacgatg tcggattatg acacagccgt gaaagctgtt
      661 gagaaaggtg ctacgatgat cacacacttg tacaatgcca tgccacagcc acatcaccgt
      721 aatgctggtg ttgtgggttt gattaattcg cctattgttg ataccccata tttcggatta
      781 atctgtgatg gtgtacatgt tgacccgtcg atggtcaacc ttgcatatag gtcgaacccc
      841 agcaagtgtg ttttggtgac tgatgctatg cacttgatag gtttgcctga tggccactac
      901 aaatgggact cgcaggttat tgtaaagact ggtgatcggt tgtatttgga gaacaccgac
      961 acgttagctg gagctgccac tacgttgccg caatgtgtgc gtaacctagt caagtggtcg
     1021 caaatcagct tgccccaagc ggtgatgact gttactaata atgctgccaa gtcaattggc
     1081 gttgaccacg agcgtgggtt tttgaatgtt gggtgtttag ctgattttgt tgttttagac
     1141 aagagtgggt ttgttcggaa agtctacaag ttgggacgtg aagttcaatc gtcagatata
     1201 cctttagata gagctactga taaattaact gctgttttat ag