isoleucine--tRNA ligase [Candida albicans SC5314].

LOCUS       XP_712413               1088 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712413
VERSION     XP_712413.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707320.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 1088)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 1088)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 1088)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 1088)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 1088)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 1088)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30368.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..1088
                     /product="isoleucine--tRNA ligase"
                     /calculated_mol_wt=125143
     Region          15..1085
                     /region_name="PLN02882"
                     /note="aminoacyl-tRNA ligase"
                     /db_xref="CDD:215477"
     CDS             1..1088
                     /gene="ILS1"
                     /locus_tag="CAALFM_C604520WA"
                     /coded_by="XM_707320.2:1..3267"
                     /note="Putative isoleucyl-tRNA synthetase, the target of
                     drugs including the cyclic beta-amino acid
                     icofungipen/PLD-118/BAY-10-8888 and mupirocin; protein
                     present in exponential and stationary growth phase yeast
                     cultures"
                     /transl_table=12
                     /db_xref="CGD:CAL0000188404"
                     /db_xref="GeneID:3645956"
ORIGIN      
        1 mslqesnnni pqgafsfpke eeavikhwdd vnafqrtlel tedlppfaff dgppfatgtp
       61 hyghilastv kdiipryatm ngyhverrfg wdthglpveh eidkklnits kedvyamgid
      121 kynaecraiv mryadewrrt ikrlgrwidm dndyktlype fmesvwwafk elfnkdavyr
      181 glrvmpysta cttplsnfea qqnykevndp altisfplld nedtclvawt ttpwtlpanl
      241 alavnpkfey vkifdeekkk nfilleslis tlykkpksak fkvvekilgk dlvglkykpl
      301 fnyfyedfkd tgfrvipady vtndsgtgiv hqapsygeed fnstkaagvi nekklppsiv
      361 ddsgrmesnv peiagmyfkd adkviikkls eegrllvntq vkhsypfcwr sdtplmyrtv
      421 pawfvrigev ipemldnvek tnwvpsnikd krfsnwiana rdwnisrnry wgtpiplwvs
      481 ddfeemvcvg siqelrelsg rdditdihre sidsitipsk kgkgqlkrie evfdcwfesg
      541 smpyaskhyp fenekkflda fpanfisegl dqtrgwfytl tvlgthlfkt apyqnvivtg
      601 ivlaadgkkm skrlknypdp tlvlekygad alrlylinsp vlraetlkfk eegvkeivss
      661 vllpwynsyk flkdaadlfk kdngkdfvyd nslhstnvmd rwllasiqsl ikfiheemtg
      721 yrlytvvprl lhfiddltnw yirfnrrrik gyasedvedt qkglntlvea lltlsramap
      781 ftpyladgiy qrikvyfkqe dlekiainpk nvdlrsvhfl sypsvrqelf dekievavar
      841 mqkvidmarn irekkmislk tplnelvvls adadllkdid slkgyisdel nvrnvvitsd
      901 eakycveysc vadwpvlgkk lksdakkvka alpkvsseev qrfaecgkit vdgidlvted
      961 lqvqrglpas kaeegqefrs hqdvliildv nlhpeleseg larelinriq rlrkkaglnt
     1021 tddvqvqyrv vkdtidlpki ikdneelllk stkypieelk eaqdsanvit deeqtindtv
     1081 fnlrllki