ubiquitin-protein ligase [Candida albicans SC5314].

LOCUS       XP_712406                776 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712406
VERSION     XP_712406.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707313.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 776)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 776)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 776)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 776)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 776)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 776)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30363.
            
            On Dec 8, 2016 this sequence version replaced XP_712406.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..776
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..776
                     /product="ubiquitin-protein ligase"
                     /calculated_mol_wt=88830
     Region          315..775
                     /region_name="COG5540"
                     /note="RING-finger-containing ubiquitin ligase
                     [Posttranslational modification, protein turnover,
                     chaperones]"
                     /db_xref="CDD:227827"
     Region          706..775
                     /region_name="RING_Ubox"
                     /note="RING finger (Really Interesting New Gene) domain
                     and U-box domain superfamily; cl17238"
                     /db_xref="CDD:473075"
     Site            order(712,715,747,749,752,755,766,769)
                     /site_type="other"
                     /note="cross-brace motif"
                     /db_xref="CDD:438111"
     CDS             1..776
                     /locus_tag="CAALFM_C604470CA"
                     /coded_by="XM_707313.2:1..2331"
                     /note="Ortholog(s) have ubiquitin-protein transferase
                     activity and role in protein ubiquitination,
                     ubiquitin-dependent protein catabolic process via the
                     multivesicular body sorting pathway"
                     /transl_table=12
                     /db_xref="CGD:CAL0000184186"
                     /db_xref="GeneID:3645985"
ORIGIN      
        1 maidrqtlvf fiimfiflsl psgneqphsd kdretlqtyq qsirnsssil qnstyasgyg
       61 nitgyqlsyk dqlqgksvad wpihefspsh pwvesqeysi lpdeisqrvr kfwgispvkd
      121 kayllnisgr adgefqlies kvkptklsip kylkeyyksr ensftsdept ednreyfkkp
      181 idkkgnvttn egvvsiaikg sqynfddpkl srfvgpedkv dnaicvsmdl dikdypeied
      241 hslvlngvyf qetgsligvt nsakfygnyg lshltmgdkn faiaktlmtq fsnmtndnel
      301 tmddmnygiv kaheqceyia fiqfaktnft herlreidee letptgrplp heipkiviee
      361 yllyspdcgk vlslkpgsvf sgkktevtra qmrnvltgil vlvgfqlflv lrqiknaqtp
      421 gqlslisskt lfllgyqdsl vaimtlllst itvelylila ciatiafisc gvfemrfmvs
      481 vlttqanerg tswweilrga naereqqvpe egpilpiand pppqetvpnq awqetsysns
      541 ifasgfsiti vsmfiifssl qwriqyrkaf eyvslvfvns fwvpqffrnt lknrrksftw
      601 efafgtsvir vlpiyyfalv kgnplrhryd pilcivvsvw lgvqllllvl qnqfgprfwi
      661 nekwlpkaye yqrllsmkdl qeegfssell enlkttmsqs edqdivtsqc mcpicmtdvd
      721 lpisvkedkl eeakrkvnik gfmitpchhi fhteclenwm kyklqcpvcr kslppi