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LOCUS XP_712313 861 aa linear PLN 18-APR-2022 ACCESSION XP_712313 VERSION XP_712313.2 DBLINK BioProject: PRJNA14005 BioSample: SAMN02953594 DBSOURCE REFSEQ: accession XM_707220.2 KEYWORDS RefSeq. SOURCE Candida albicans SC5314 ORGANISM Candida albicans SC5314 Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade; Candida. REFERENCE 1 (residues 1 to 861) AUTHORS Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G. TITLE Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure JOURNAL Genome Biol. 14 (9), R97 (2013) PUBMED 24025428 REFERENCE 2 (residues 1 to 861) AUTHORS van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D., Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B., Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T. TITLE Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes JOURNAL Genome Biol. 8 (4), R52 (2007) PUBMED 17419877 REFERENCE 3 (residues 1 to 861) AUTHORS Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S., Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T., Davis,R.W. and Scherer,S. TITLE The diploid genome sequence of Candida albicans JOURNAL Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004) PUBMED 15123810 REFERENCE 4 (residues 1 to 861) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (15-APR-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 5 (residues 1 to 861) AUTHORS Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G. TITLE Direct Submission JOURNAL Submitted (04-OCT-2016) Department of Genetics, Candida Genome Database, Stanford University, Mail Stop-5120, Stanford, CA 94305, USA REFERENCE 6 (residues 1 to 861) CONSRTM Candida Genome Database TITLE Direct Submission JOURNAL Submitted (30-SEP-2016) Department of Genetics, Candida Genome Database, Stanford University, Mail Stop-5120, Stanford, CA 94305, USA REMARK Sequence and annotation update by submitter COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to AOW29984. On Dec 8, 2016 this sequence version replaced XP_712313.1. ##Genome-Annotation-Data-START## Annotation Provider :: CGD Annotation Status :: Full annotation Annotation Version :: A22-s07-m01-r01 URL :: http://www.candidagenome.org/ ##Genome-Annotation-Data-END## Method: conceptual translation. FEATURES Location/Qualifiers source 1..861 /organism="Candida albicans SC5314" /strain="SC5314" /host="Homo sapiens" /culture_collection="ATCC:MYA-2876" /db_xref="taxon:237561" /chromosome="6" /haplotype="A" /geo_loc_name="USA: New York" /collected_by="Margarita Silva-Hutner" Protein 1..861 /product="protein kinase" /calculated_mol_wt=96333 Region 44..322 /region_name="STKc_PDK1" /note="Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1; cd05581" /db_xref="CDD:270733" Site order(51..55,59,72,74,108,124..125,127,131,133,170,172, 174..175,177,187..188,191,226..231,258,264,267) /site_type="active" /db_xref="CDD:270733" Site order(51..54,57,59,72,74,93,108,124..127,130..131, 174..175,177,187..188) /site_type="other" /note="ATP binding site [chemical binding]" /db_xref="CDD:270733" Site order(55,131,133,170,172,174,191,226..231,258,264,267) /site_type="other" /note="polypeptide substrate binding site [polypeptide binding]" /db_xref="CDD:270733" Site order(187..197,223..231) /site_type="other" /note="activation loop (A-loop)" /db_xref="CDD:270733" CDS 1..861 /gene="PKH3" /locus_tag="CAALFM_C600350WA" /coded_by="XM_707220.2:1..2586" /note="Ortholog(s) have protein kinase activity and role in MAPK cascade involved in cell wall organization or biogenesis" /transl_table=12 /db_xref="CGD:CAL0000179865" /db_xref="GeneID:3646075" ORIGIN 1 msglehlqnl siqpsnrstq qqqtnsqpqs qysqsaakrr sardyqfgak igegsystvy 61 saldkytnrt yaikvlskrh ivkenkikyv niekttlnrl gqqhpgivql yytfqdessl 121 ffvldfaeyg ellsiirkfg slsesvskfy mcqiidavrf ihskgvihrd lkpenilvgh 181 dfnlkitdfg aakllgnhee fngekidyns vdaspevsdt drkgsfvgta eyvspellkh 241 nicgfesdiw aigcilyqff ngvppfkgst eyltfekiin vdysykspip lppdviqlid 301 silisepsar atiphimssr wfsdipwddq nfiwhrkvpr feafgaitps pamppmmkng 361 tnrnvnksns yhqlqsqisa sefgfipsia akksykpptm iknnvampal nqttynhnyq 421 qhvplpppvs sqpltqqnvp qqiqpqrsgs aqtpqfapvs assrqpvgnm qtrqaapqvl 481 vqqktppfpk eknstpnlrd ntsfaqmapr rngeipgqpq qqiplpksqq spqpqpkaqy 541 qsqqqkqsed irgskntsan aaaaafatkn lpqpnhktsk dsstpppppp lppkikkvqe 601 nfikfnevsg llkpdekilk mdnliksvls krylnkpeyq vlddsvldel tskyasilkq 661 eskavitivt nmarvffida flnvmlvdlk ankgadysmy dyefentvde dgnllskqde 721 tfgyliieli kdggdlvflq rvsdeqrlrl tnavkvldkk geevvvgssh gwidclliar 781 eisieqsedn kkprsvssss nvsinevkse kakkkkssls nkkprskkkg tssngtpqtt 841 ptptqhsnfa faaaaavhhq k