Candida albicans SC5314 protein kinase (PKH3), partial mRNA.

LOCUS       XM_707220               2586 bp    mRNA    linear   PLN 18-APR-2022
ACCESSION   XM_707220
VERSION     XM_707220.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (bases 1 to 2586)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (bases 1 to 2586)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (bases 1 to 2586)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (bases 1 to 2586)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 2586)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (bases 1 to 2586)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NC_032094).
            
            On Dec 8, 2016 this sequence version replaced XM_707220.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..2586
                     /organism="Candida albicans SC5314"
                     /mol_type="mRNA"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     gene            <1..>2586
                     /gene="PKH3"
                     /locus_tag="CAALFM_C600350WA"
                     /db_xref="GeneID:3646075"
     CDS             1..2586
                     /gene="PKH3"
                     /locus_tag="CAALFM_C600350WA"
                     /note="Ortholog(s) have protein kinase activity and role
                     in MAPK cascade involved in cell wall organization or
                     biogenesis"
                     /codon_start=1
                     /transl_table=12
                     /product="protein kinase"
                     /protein_id="XP_712313.2"
                     /db_xref="CGD:CAL0000179865"
                     /db_xref="GeneID:3646075"
                     /translation="MSGLEHLQNLSIQPSNRSTQQQQTNSQPQSQYSQSAAKRRSARD
                     YQFGAKIGEGSYSTVYSALDKYTNRTYAIKVLSKRHIVKENKIKYVNIEKTTLNRLGQ
                     QHPGIVQLYYTFQDESSLFFVLDFAEYGELLSIIRKFGSLSESVSKFYMCQIIDAVRF
                     IHSKGVIHRDLKPENILVGHDFNLKITDFGAAKLLGNHEEFNGEKIDYNSVDASPEVS
                     DTDRKGSFVGTAEYVSPELLKHNICGFESDIWAIGCILYQFFNGVPPFKGSTEYLTFE
                     KIINVDYSYKSPIPLPPDVIQLIDSILISEPSARATIPHIMSSRWFSDIPWDDQNFIW
                     HRKVPRFEAFGAITPSPAMPPMMKNGTNRNVNKSNSYHQLQSQISASEFGFIPSIAAK
                     KSYKPPTMIKNNVAMPALNQTTYNHNYQQHVPLPPPVSSQPLTQQNVPQQIQPQRSGS
                     AQTPQFAPVSASSRQPVGNMQTRQAAPQVLVQQKTPPFPKEKNSTPNLRDNTSFAQMA
                     PRRNGEIPGQPQQQIPLPKSQQSPQPQPKAQYQSQQQKQSEDIRGSKNTSANAAAAAF
                     ATKNLPQPNHKTSKDSSTPPPPPPLPPKIKKVQENFIKFNEVSGLLKPDEKILKMDNL
                     IKSVLSKRYLNKPEYQVLDDSVLDELTSKYASILKQESKAVITIVTNMARVFFIDAFL
                     NVMLVDLKANKGADYSMYDYEFENTVDEDGNLLSKQDETFGYLIIELIKDGGDLVFLQ
                     RVSDEQRLRLTNAVKVLDKKGEEVVVGSSHGWIDCLLIAREISIEQSEDNKKPRSVSS
                     SSNVSINEVKSEKAKKKKSSLSNKKPRSKKKGTSSNGTPQTTPTPTQHSNFAFAAAAA
                     VHHQK"
     misc_feature    130..966
                     /gene="PKH3"
                     /locus_tag="CAALFM_C600350WA"
                     /note="Catalytic domain of the Serine/Threonine Kinase,
                     Phosphoinositide-dependent kinase 1; Region: STKc_PDK1;
                     cd05581"
                     /db_xref="CDD:270733"
     misc_feature    order(151..165,175..177,214..216,220..222,322..324,
                     370..375,379..381,391..393,397..399,508..510,514..516,
                     520..525,529..531,559..564,571..573,676..693,772..774,
                     790..792,799..801)
                     /gene="PKH3"
                     /locus_tag="CAALFM_C600350WA"
                     /note="active site"
                     /db_xref="CDD:270733"
     misc_feature    order(151..162,169..171,175..177,214..216,220..222,
                     277..279,322..324,370..381,388..393,520..525,529..531,
                     559..564)
                     /gene="PKH3"
                     /locus_tag="CAALFM_C600350WA"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:270733"
     misc_feature    order(163..165,391..393,397..399,508..510,514..516,
                     520..522,571..573,676..693,772..774,790..792,799..801)
                     /gene="PKH3"
                     /locus_tag="CAALFM_C600350WA"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:270733"
     misc_feature    order(559..591,667..693)
                     /gene="PKH3"
                     /locus_tag="CAALFM_C600350WA"
                     /note="activation loop (A-loop); other site"
                     /db_xref="CDD:270733"
ORIGIN      
        1 atgtcagggt tagaacatct acagaactta tctatccagc cgtcaaatcg gagtactcag
       61 cagcaacaga ccaattctca accacaatca caatactcac aactggcggc caaacgaaga
      121 tcagcaagag actatcaatt tggagcgaaa ataggagaag gatcatattc cacagtatac
      181 tctgcattgg ataaatacac caatagaact tatgctatta aagtgttatc gaaacgacat
      241 atagtgaaag agaacaaaat taaatatgtc aatattgaaa agaccacttt gaacagattg
      301 ggtcaacaac atcccgggat tgttcaatta tattatactt tccaagatga gagtagcttg
      361 ttttttgttt tggattttgc agaatatggg gagttgttgt caatcattag aaaatttgga
      421 tctttatctg aatccgtact gaaattttac atgtgtcaaa taatagatgc agttaggttt
      481 attcatctga aaggggtgat ccatcgagat ttgaaaccag agaatatttt agttggacat
      541 gactttaatt taaaaatcac cgattttgga gcagccaagt tattaggcaa tcacgaagag
      601 ttcaatggcg agaaaataga ctataattca gtagatgcca gtccagaggt atctgatact
      661 gatcgaaagg gatcgtttgt gggcacagct gaatacgttt ctccggaatt acttaagcac
      721 aatatatgcg gttttgaatc tgacatttgg gctattgggt gtatattata tcaattcttt
      781 aatggcgttc cgccgtttaa aggaagcacc gagtacttga cttttgaaaa gattataaat
      841 gtggactatt catacaaatc acccataccc ttaccgccag acgtgatcca attgattgat
      901 ctgatactta tttctgaacc atctgcacga gcaacaatcc cacatatcat gtcatcaagg
      961 tggttttctg acataccttg ggacgaccaa aattttatat ggcataggaa ggttccccgg
     1021 tttgaagcat ttggcgccat tacaccgtca ccagcaatgc ctccaatgat gaagaacgga
     1081 accaacagaa atgtcaataa atcaaactct taccaccaat tgcagtcaca gatactggcc
     1141 tctgagtttg gatttattcc ttcaattgca gcaaaaaaat cgtacaaacc accaacaatg
     1201 ataaagaata acgtagcaat gcctgcgttg aatcaaacta catataatca taactaccaa
     1261 caacatgtac cgctccctcc tccagtatcg tcacaaccat taacacaaca gaacgtaccg
     1321 caacaaattc aaccgcaaag aagtggttct gcacaaacgc cccagtttgc accagtttcg
     1381 gcttctagcc gacaacctgt tggtaacatg caaactagac aagctgcacc acaagtattg
     1441 gtacaacaaa aaactccccc tttcccaaag gagaagaaca gtacaccaaa tttaagggac
     1501 aatacatctt ttgcacaaat ggctcccaga aggaatgggg agatacctgg acaacctcaa
     1561 caacaaatac cattgccaaa atcgcaacaa tcaccacaac cacaaccaaa agctcaatat
     1621 caactgcaac agcaaaaaca actggaagat ataaggggtt ctaaaaatac atcagcaaat
     1681 gcagcagccg cagcttttgc tacaaaaaat ttaccacagc caaatcacaa aacatctaag
     1741 gactcatcaa caccgccacc accaccacca ctaccaccaa agatcaaaaa agtgcaggaa
     1801 aatttcatta aatttaatga agtctctggg ctattgaagc cggatgaaaa gattttaaaa
     1861 atggacaatt tgatcaagct ggtattgagc aagagatatc taaataaacc cgaataccag
     1921 gttttagatg attctgtttt ggatgaattg acatccaagt acgccagtat ccttaaacaa
     1981 gaatctaaag cagttatcac tattgtcact aacatggctc gtgtattctt tatagatgca
     2041 tttttgaatg tcatgctagt ggacttgaag gcaaacaagg gggcagacta tctgatgtat
     2101 gattatgaat ttgaaaatac agttgatgaa gatggtaatt tactttcgaa acaggatgaa
     2161 acgtttggat acttgataat cgaattgatc aaagatggtg gggatttggt attcctacag
     2221 agagttagcg acgagcaaag attaagattg accaatgctg tcaaggtttt agataaaaaa
     2281 ggcgaagaag tagttgttgg atcaagtcat ggatggattg actgcttgtt aatagctcga
     2341 gagatatcaa tcgagcaaag cgaagataac aaaaagccac gatctgtgag ctcgtcatct
     2401 aatgtaagta ttaatgaagt taaatcagag aaagccaaaa aaaagaaact gtcattatca
     2461 aataaaaagc ccagatccaa gaagaaggga acaagctcta atgggactcc tcaaacaaca
     2521 ccaaccccaa ctcaacattc aaactttgca tttgcagcag cagcagctgt gcaccaccaa
     2581 aaataa