Cph2p [Candida albicans SC5314].

LOCUS       XP_712305                853 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712305
VERSION     XP_712305.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707212.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 853)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 853)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 853)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 853)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 853)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 853)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW29977.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..853
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..853
                     /product="Cph2p"
                     /calculated_mol_wt=95916
     Region          207..292
                     /region_name="bHLH_SF"
                     /note="basic Helix Loop Helix (bHLH) domain superfamily;
                     cl00081"
                     /db_xref="CDD:469605"
     Site            order(214..215,217,222,259..260)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:381405"
     Site            order(220..221,224..225,227..228,232,260..261,264..265,
                     268,270..271,274..275)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:381405"
     CDS             1..853
                     /gene="CPH2"
                     /locus_tag="CAALFM_C600280WA"
                     /coded_by="XM_707212.2:1..2562"
                     /note="Myc-bHLH transcription factor; promotes hyphal
                     growth; directly regulates Tec1 to induce hypha-specific
                     genes; probably homodimeric, phosphorylated; required for
                     colonization of the mouse GI tract; rat catheter and
                     Spider biofilm induced"
                     /transl_table=12
                     /db_xref="CGD:CAL0000181382"
                     /db_xref="GeneID:3646067"
ORIGIN      
        1 mlsqydeqla agdnngfnkq gnatlysfdf vdaddfldsi sgalpnnghn nvnpntndis
       61 fedmnimnpn iyspvsaasg ddftqssgqp misegsnytg qnftdylsdn slegydknts
      121 rplhevdigf snkrsnstst gslshneeit pishysvdsi vtspeppink qgdfppikrt
      181 ttvsstnsit nttkkpakvt kpkskdknsh nmiekkyrtn intkilalrd avpalriaag
      241 cddvsiadle gltpasklnk asvltkatey ikhlesknfi lkqqnielhr liqhanmnpk
      301 slppppqqmq appqpgfgfy ppqnqsfnvt pasqypspqq qvsptqqqtv hhppqpnryl
      361 lggmaavmgt slfggsgend frslsalpfs ylfpnailnp spltiqlwtl tkvllvvgsl
      421 asifipmykq aqlkkedkpn tipetslldw ilisigfktp aklsvskrda iisnlqggnd
      481 wsqlvsdyfy lagceinfen cflslvlgti irhrfpvvat ilnhylsmke alllnldykg
      541 fskslirlnq liskvdgvsi festnlttrl tnvftnnrin anivdgqnhv kyiefyqrni
      601 ndyyaivfnw rllefiheln vtyleqlndd qsqvltdlki ieaffgeqdn klfgyyqlft
      661 silnanyapy lfeslkdkve sslekfriay egidltdhei hntssedeye qespvvykye
      721 ptlksqksli sslnlvneee fiiltcslti yyyknkeydr alkllnylrl dndsktlsll
      781 tftslitlin elipgkiedn vnldsairic rdwlenpdlt qymdedikle lkkivvtkgm
      841 ivngidvnes dee