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uncharacterized protein CAALFM_C600190WA [Candida albicans SC5314].


LOCUS       XP_712295                409 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712295
VERSION     XP_712295.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707202.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 409)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 409)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 409)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 409)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 409)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 409)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW29969.
            
            On Dec 8, 2016 this sequence version replaced XP_712295.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..409
                     /product="uncharacterized protein"
                     /calculated_mol_wt=46102
     Region          3..51
                     /region_name="RTT106_N"
                     /note="histone chaperone RTT106, regulator of Ty1
                     transposition protein 106; N-terminal homodimerization
                     domain; cl16939"
                     /db_xref="CDD:450127"
     Site            order(5,9..10,13,16..17,20..21,23..24,27..28,30..31,
                     34..35,37..39,42)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:211429"
     Region          54..213
                     /region_name="PH_18"
                     /note="Pleckstrin homology domain; pfam18469"
                     /db_xref="CDD:436524"
     Region          241..335
                     /region_name="PH2-like_Rtt106"
                     /note="Pleckstrin homology-like domain, repeat 2, of
                     Histone chaperone RTT106 (regulator of Ty1 transposition
                     protein 106); cd13304"
                     /db_xref="CDD:241458"
     Site            order(251,254,276..277)
                     /site_type="other"
                     /note="dsDNA binding site [nucleotide binding]"
                     /db_xref="CDD:241458"
     Site            order(255,321)
                     /site_type="other"
                     /note="negative patch"
                     /db_xref="CDD:241458"
     Site            order(262..263,285,332,335)
                     /site_type="other"
                     /note="K56ac binding site [polypeptide binding]"
                     /db_xref="CDD:241458"
     Site            292..301
                     /site_type="other"
                     /note="H3-H4 binding site [polypeptide binding]"
                     /db_xref="CDD:241458"
     Site            order(296,299)
                     /site_type="other"
                     /note="H3 histone binding site [polypeptide binding]"
                     /db_xref="CDD:241458"
     CDS             1..409
                     /locus_tag="CAALFM_C600190WA"
                     /coded_by="XM_707202.2:1..1230"
                     /note="Ortholog of S. cerevisiae Rtt106; histone chaperone
                     that regulates chromatin structure in transcribed and
                     silenced chromosomal regions; affects transcriptional
                     elongation; Hap43-repressed; Spider biofilm repressed"
                     /transl_table=12
                     /db_xref="CGD:CAL0000189137"
                     /db_xref="GeneID:3646080"
ORIGIN      
        1 mdsawvqqlp pelqndikav vekdqssfaa fdnlhafltg gttkkrklna epeeippeti
       61 ifeineisfy spvrkrmnlt lhlveedgnp spalsivnps nnipeltftg ldqavklcll
      121 lpilgnttnt qkkaicylcf wmhdenmskd pivcqmnldl vkksmikngk lpadieskfi
      181 tprdalplnp iqeriidyfk rqfqlcgism mnympcvsif rntfslnddn aiamntdgas
      241 qpalvmvnch kgakegvlil lqanktnpah iifgfkkpil vfeasqvlht sysnitrqtf
      301 slnvvvlnkk qeqrelefgm idekfykvid dfiklqgind atfnqeesgd dsieivhvnn
      361 ndddddeedd dfqsedsgsd veeeynsdln eplaaheedg vfergieie