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uncharacterized protein CAALFM_C604370WA [Candida albicans SC5314].


LOCUS       XP_712108                879 aa            linear   PLN 18-APR-2022
ACCESSION   XP_712108
VERSION     XP_712108.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_707015.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 879)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 879)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 879)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 879)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 879)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 879)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30355.
            
            On Dec 8, 2016 this sequence version replaced XP_712108.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..879
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..879
                     /product="uncharacterized protein"
                     /calculated_mol_wt=98954
     Region          101..602
                     /region_name="ClC_3_like"
                     /note="ClC-3-like chloride channel proteins. This CD
                     includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was
                     initially cloned from rat kidney. Expression of ClC-3
                     produces outwardly-rectifying Cl currents that are
                     inhibited by protein kinase C activation. It has...;
                     cd03684"
                     /db_xref="CDD:239656"
     Site            order(195..199,239..243,492..496,595)
                     /site_type="active"
                     /note="putative Cl- selectivity filter [active]"
                     /db_xref="CDD:239656"
     Site            241
                     /site_type="active"
                     /note="putative pore gating glutamate residue [active]"
                     /db_xref="CDD:239656"
     Site            300
                     /site_type="active"
                     /note="putative H+/Cl- coupling transport residue
                     [active]"
                     /db_xref="CDD:239656"
     CDS             1..879
                     /locus_tag="CAALFM_C604370WA"
                     /coded_by="XM_707015.2:1..2640"
                     /note="Has domain(s) with predicted ion channel activity,
                     voltage-gated chloride channel activity, role in chloride
                     transport, transmembrane transport and membrane
                     localization"
                     /transl_table=12
                     /db_xref="CGD:CAL0000193876"
                     /db_xref="GeneID:3646294"
ORIGIN      
        1 msgldrgant atttttssss ttssssysit ystneipilt ysnnnnnnsp hihqssevhe
       61 tshhsqyeen tfidwskesi iisrnpsvfl tnkwiilifs aiilgyftsa idliqvslnd
      121 fkkgicfssk dswtllnpym tcpvedwynw dqifftirnp ivkfiinfpi ylilalafgi
      181 iagyltynra ymirqsgipe ikliisgfnl kidqylgfkt llsksialif vvssglwlgk
      241 egplvhiscc vfniiyeiis kyysnqneai rrelltaata tgisvafnsp iggvlfvles
      301 mpsyfiptri mwnsfvsatv atiiltgfki ftdgrnfneq vlfqvnfgnf swlfveiipf
      361 imlgimggvy ghyfikfngk fsnikirsli rhrlcnllkv dykygsilei llivlittii
      421 nfpfeisklp lnallnllfk sctkdndnsn lstskdficq dsngvalfkl lyimiegfwl
      481 tcytfgldlp ggilmpslvm gamtgrflgi itqaiqskfn weslatctad sclvspssya
      541 vigaasfmtg vtkltmsvvv imfemtgavt yvlpimggvm tskfvsdwlt pnniydtwlq
      601 nnfnqssdgv egvttnnhln snfydngnql inqgkgtgli sfqnltstik sklpninias
      661 smiplldvkc lcllpdqeqe qftlnslnsf inndchegyp miinynnpii vgyipksqll
      721 nqlflslsnr eidsnspisf qinhgvdipe rveqllsqrk qpqvvsinvh piqstliine
      781 ktpilliiem feklhlnsli ivsnqdetsm tgfidrfiln dliidkfekl vdklndyqvi
      841 qqfdieenag rvemtefdyd ndedddmtri drksielit