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long-chain fatty acid transporter [Candida albicans SC5314].


LOCUS       XP_711325                650 aa            linear   PLN 18-APR-2022
ACCESSION   XP_711325
VERSION     XP_711325.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_706233.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 650)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 650)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 650)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 650)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 650)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 650)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30020.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..650
                     /product="long-chain fatty acid transporter"
                     /calculated_mol_wt=73150
     Region          94..616
                     /region_name="Adenylate forming domain, Class I
                     superfamily"
                     /note="This family includes acyl- and aryl-CoA ligases, as
                     well as the adenylation domain of nonribosomal peptide
                     synthetases and firefly luciferases. The adenylate-forming
                     enzymes catalyze an ATP-dependent two-step reaction to
                     first activate a carboxylate...; cl17068"
                     /db_xref="CDD:473059"
     Site            order(240,243..248,250..251)
                     /site_type="other"
                     /note="acyl-activating enzyme (AAE) consensus motif"
                     /db_xref="CDD:341228"
     Site            order(243,358..359,379..384,495,507,510,521,603)
                     /site_type="other"
                     /note="AMP binding site [chemical binding]"
                     /db_xref="CDD:341228"
     Site            order(243,283..284,340,342..343,346,358..359,379..384,495,
                     507,510,518..521,585)
                     /site_type="active"
                     /db_xref="CDD:341228"
     Site            order(283,342..343,346,358,518..520,576,585)
                     /site_type="other"
                     /note="CoA binding site [chemical binding]"
                     /db_xref="CDD:341228"
     CDS             1..650
                     /gene="FAT1"
                     /locus_tag="CAALFM_C600740WA"
                     /coded_by="XM_706233.2:1..1953"
                     /note="Predicted enzyme of sphingolipid biosynthesis;
                     upregulated in biofilm"
                     /transl_table=12
                     /db_xref="CGD:CAL0000176828"
                     /db_xref="GeneID:3647083"
ORIGIN      
        1 msglelavaa vlgsqlleak ylisddlsla stvarnalpy lwkssrgras ywysfedsal
       61 rysnnkalaf prpkknppkp qvdengysiy ddqfdleeft ykelydmvlr ysyilkneyg
      121 vtsndtigva cmnkplfiil wlalwnigal paflnfntkd kplvhclkia nvsqvfvdpd
      181 cdkpirdtes qiaeelpntk ihyidelalf drlrlkstpk hrakdstrrp qdtdssacal
      241 iytsgttglp kagimswrka fmasvifghi mkikenssvl tamplyhsta amlgvcptli
      301 vggcvtvsqk fsatsfwtqa rlcgathiqy vgevcrylln skphpdqdrh nvriaygngl
      361 rrdiwsefks rfhidgigef yaatespiat tnlqygeygv gacrkygsii nlflstqqkl
      421 akmdpedese iwrdpktglc teaaynepge lmmrilnpqd ieksfqgyyg nksatnskil
      481 tnvfskgdaw yrsgdllkmd edkllyfvdr lgdtfrwkse nvsatevene lmgsktlkqs
      541 vvvgvkvpnh egracfavce pkdelqheei lkaihehvtk slpsyaqpaf lkigaieash
      601 nhkvpknqfk nqklpkgedg kemiywlngd kytelteddw ssicagkakl