phosphoglycerate kinase [Candida albicans SC5314].

LOCUS       XP_711323                417 aa            linear   PLN 18-APR-2022
ACCESSION   XP_711323
VERSION     XP_711323.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_706231.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 417)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 417)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 417)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 417)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 417)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 417)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30021.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..417
                     /product="phosphoglycerate kinase"
                     /calculated_mol_wt=45049
     Region          3..416
                     /region_name="PTZ00005"
                     /note="phosphoglycerate kinase; Provisional"
                     /db_xref="CDD:173310"
     Site            order(24,26,39,63,122)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:238195"
     Site            order(200..203,391..393)
                     /site_type="other"
                     /note="hinge regions"
                     /db_xref="CDD:238195"
     Site            order(238,312,336,338,340..343,373..375)
                     /site_type="other"
                     /note="ADP binding site [chemical binding]"
                     /db_xref="CDD:238195"
     Site            374
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:238195"
     CDS             1..417
                     /gene="PGK1"
                     /locus_tag="CAALFM_C600750CA"
                     /coded_by="XM_706231.2:1..1254"
                     /note="Phosphoglycerate kinase; localizes to cell wall and
                     cytoplasm; antigenic in murine/human infection; flow model
                     biofilm, Hog1-, Hap43-, GCN-induced; repressed upon
                     phagocytosis; repressed in Spider biofilms by Bcr1, Ndt80,
                     Rob1, Brg1"
                     /transl_table=12
                     /db_xref="CGD:CAL0000184891"
                     /db_xref="GeneID:3647081"
ORIGIN      
        1 mslsnklsvk dldvagkrvf irvdfnvpld gktitnnqri vaalptikyv eehkpkyivl
       61 ashlgrpnge rndkyslapv atelekllgq kvtflndcvg pevtkavena kdgeifllen
      121 lryhieeegs skdkdgkkvk adpeavkkfr qeltsladvy indafgtahr ahssmvglev
      181 pqraagflms keleyfakal enperpflai lggakvsdki qlidnlldkv dmlivgggma
      241 ftfkkilnkm pigdslfdea gaknvehlve kakknnveli lpvdfvtadk fdkdaktssa
      301 tdaegipdnw mgldcgpksv elfqqavaka ktivwngppg vfefekfang tkslldaavk
      361 saengnivii gggdtatvak kygvveklsh vstgggasle llegkdlpgv valsnkn