RNA lariat debranching enzyme [Candida albicans SC5314].

LOCUS       XP_710844                465 aa            linear   PLN 18-APR-2022
ACCESSION   XP_710844
VERSION     XP_710844.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_705752.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 465)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 465)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 465)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 465)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 465)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 465)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30141.
            
            On Dec 8, 2016 this sequence version replaced XP_710844.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..465
                     /product="RNA lariat debranching enzyme"
                     /calculated_mol_wt=54154
     Region          7..266
                     /region_name="MPP_Dbr1_N"
                     /note="Dbr1 RNA lariat debranching enzyme, N-terminal
                     metallophosphatase domain; cd00844"
                     /db_xref="CDD:277322"
     Site            order(12,14,38,83..84,175,227,229,247)
                     /site_type="active"
                     /db_xref="CDD:277322"
     Site            order(38,83,175,227)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:277322"
     Region          314..455
                     /region_name="DBR1"
                     /note="Lariat debranching enzyme, C-terminal domain;
                     pfam05011"
                     /db_xref="CDD:461518"
     CDS             1..465
                     /gene="DBR1"
                     /locus_tag="CAALFM_C602050WA"
                     /coded_by="XM_705752.2:1..1398"
                     /note="Debranchase; homozygous mutant accumulates lariat
                     intermediates of mRNA splicing; rat catheter biofilm
                     repressed"
                     /transl_table=12
                     /db_xref="CGD:CAL0000191567"
                     /db_xref="GeneID:3647560"
ORIGIN      
        1 msntlkiaie gcchgelndi ynsipdiesl dlllicgdfq slrnkcdlqs lnvplkyqrm
       61 adfheyysgk rkapvltifi ggnhecssyl qelkyggwva pniyylgefg siwykglqit
      121 gwsgifnyht fianniemek lpfdsrtirs vyhqklanfl kmymmnhdmd ivlshdwpvg
      181 iekygnvkrl lklkpffrdd iqrgqlgspl nkflihylrp rywfsghlhv kfearivdlv
      241 rstdkkksat tvdlitesnk eeisldmdde eeeeggnvre vsfeekfyfk qhsnpakrpk
      301 ndltperdvc ehateflald kcgkrrqfld iktievhnts hpsfinagkl yyskrsiain
      361 kvvekylndn rqdftelntk qilsnpqqfp lvnelmpiie ndfksmqkni tdedffmvpe
      421 nfqtiaptdd ehtesklkyy pnnqtseyce kfgipklvls kesdq