mRNA-binding ubiquitin-specific protease [Candida albicans SC5314].

LOCUS       XP_710490                660 aa            linear   PLN 18-APR-2022
ACCESSION   XP_710490
VERSION     XP_710490.2
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_705398.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 660)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 660)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 660)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 660)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 660)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 660)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW29967.
            
            On Dec 8, 2016 this sequence version replaced XP_710490.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..660
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..660
                     /product="mRNA-binding ubiquitin-specific protease"
                     /calculated_mol_wt=75012
     Region          289..657
                     /region_name="UCH"
                     /note="Ubiquitin carboxyl-terminal hydrolase; pfam00443"
                     /db_xref="CDD:425685"
     Site            order(293,298,613,629)
                     /site_type="active"
                     /db_xref="CDD:239072"
     CDS             1..660
                     /locus_tag="CAALFM_C600170CA"
                     /coded_by="XM_705398.2:1..1983"
                     /note="Ortholog(s) have mRNA binding, ubiquitin-specific
                     protease activity and role in protein deubiquitination,
                     regulation of ER to Golgi vesicle-mediated transport,
                     regulation of response to osmotic stress, ribophagy"
                     /transl_table=12
                     /db_xref="CGD:CAL0000199093"
                     /db_xref="GeneID:3647903"
ORIGIN      
        1 mtssssnsgs srfrgdaasf spsqypnyhq qqfhpqqyma qqipaqqqfy yqfpqtypmm
       61 mnqmypvfpy ppdpffqqqq qqqqqqqqqq qfvmqpqyiy hpppkppktn kppkvngsap
      121 ppkielvdlp lyintsktef lqrysitqes rsidelqran tleeynentn rliistnvmk
      181 iidendhktt itngqpeepk paakavappv pisnwasflq stapptpkki akpkppptpp
      241 tpvqavtpvp qfdmsnesaq plgtlllkim fdsnysvfss lptfdikprg ltntgnicym
      301 nsilqilihc epfnrllkli etksigslgp sstplldati iffnqfqenv kgaispesfy
      361 asltkldkfs hlkwgqqeda eeflgyyldg lneeflgaik qlntpqidsl iqvyaqdhda
      421 eatakfkfnv kstikriknd aeaddgewnq vnkkknsttt kieidptpln mifggefksv
      481 vtipkqsssf qksitldpfq hvqldvssad tiedaikhln esesisytnn nkeiqvkkqt
      541 fieklpnvli ihlkrfsylk dqeigveklr kkvdynhdli ipkevmardt gmpikyqlvs
      601 vvyhhgssad aghytsdiyn agqwwriddt avkqiqneev lnagteenik nayillyrri