Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

27S pre-rRNA (guanosine2922-2'-O)-methyltransferase [Candida


LOCUS       XP_710224                845 aa            linear   PLN 18-APR-2022
            albicans SC5314].
ACCESSION   XP_710224
VERSION     XP_710224.1
DBLINK      BioProject: PRJNA14005
            BioSample: SAMN02953594
DBSOURCE    REFSEQ: accession XM_705132.2
KEYWORDS    RefSeq.
SOURCE      Candida albicans SC5314
  ORGANISM  Candida albicans SC5314
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Pichiomycetes; Debaryomycetaceae; Candida/Lodderomyces clade;
            Candida.
REFERENCE   1  (residues 1 to 845)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Assembly of a phased diploid Candida albicans genome facilitates
            allele-specific measurements and provides a simple model for repeat
            and indel structure
  JOURNAL   Genome Biol. 14 (9), R97 (2013)
   PUBMED   24025428
REFERENCE   2  (residues 1 to 845)
  AUTHORS   van het Hoog,M., Rast,T.J., Martchenko,M., Grindle,S., Dignard,D.,
            Hogues,H., Cuomo,C., Berriman,M., Scherer,S., Magee,B.B.,
            Whiteway,M., Chibana,H., Nantel,A. and Magee,P.T.
  TITLE     Assembly of the Candida albicans genome into sixteen supercontigs
            aligned on the eight chromosomes
  JOURNAL   Genome Biol. 8 (4), R52 (2007)
   PUBMED   17419877
REFERENCE   3  (residues 1 to 845)
  AUTHORS   Jones,T., Federspiel,N.A., Chibana,H., Dungan,J., Kalman,S.,
            Magee,B.B., Newport,G., Thorstenson,Y.R., Agabian,N., Magee,P.T.,
            Davis,R.W. and Scherer,S.
  TITLE     The diploid genome sequence of Candida albicans
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (19), 7329-7334 (2004)
   PUBMED   15123810
REFERENCE   4  (residues 1 to 845)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 845)
  AUTHORS   Muzzey,D., Schwartz,K., Weissman,J.S. and Sherlock,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
REFERENCE   6  (residues 1 to 845)
  CONSRTM   Candida Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2016) Department of Genetics, Candida Genome
            Database, Stanford University, Mail Stop-5120, Stanford, CA 94305,
            USA
  REMARK    Sequence and annotation update by submitter
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to AOW30336.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: CGD
            Annotation Status   :: Full annotation
            Annotation Version  :: A22-s07-m01-r01
            URL                 :: http://www.candidagenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..845
                     /organism="Candida albicans SC5314"
                     /strain="SC5314"
                     /host="Homo sapiens"
                     /culture_collection="ATCC:MYA-2876"
                     /db_xref="taxon:237561"
                     /chromosome="6"
                     /haplotype="A"
                     /geo_loc_name="USA: New York"
                     /collected_by="Margarita Silva-Hutner"
     Protein         1..845
                     /product="27S pre-rRNA
                     (guanosine2922-2'-O)-methyltransferase"
                     /calculated_mol_wt=96689
     Region          1..204
                     /region_name="RlmE"
                     /note="23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ
                     [Translation, ribosomal structure and biogenesis];
                     COG0293"
                     /db_xref="CDD:440062"
     Region          246..403
                     /region_name="DUF3381"
                     /note="Domain of unknown function (DUF3381); pfam11861"
                     /db_xref="CDD:463375"
     Region          624..841
                     /region_name="Spb1_C"
                     /note="Spb1 C-terminal domain; pfam07780"
                     /db_xref="CDD:462264"
     CDS             1..845
                     /gene="SPB1"
                     /locus_tag="CAALFM_C604160CA"
                     /coded_by="XM_705132.2:1..2538"
                     /note="Putative AdoMet-dependent methyltransferase;
                     Hap43-induced; repressed by prostaglandins; possibly
                     essential gene, disruptants not obtained by UAU1 method;
                     Spider biofilm induced"
                     /transl_table=12
                     /db_xref="CGD:CAL0000201177"
                     /db_xref="GeneID:3648179"
ORIGIN      
        1 mgkqqkkhsk grldryyyla kekgyrarss fkiiqineky ghflekskvv idlcaapgsw
       61 cqvasqlcpi nsliigvdiv pikplpnvit fqsdittedc rsrlrghmkt wkadtvlhdg
      121 apnvglgwvq daftqsqltl qalklavenl taggtfvtki frsrdynnlm wvfqqlfekv
      181 eatkppasrn vsaeifvvck gfkapkkldp rlldpkevfe elgggneskq nneakifnpe
      241 kfssqrqrqg yqegdytlfh tmpimdfikq ddpinqlgsl nkfdlpapkd ddnddddhdh
      301 ewkilsklkl ctpellecik dlkvlgrkef kmilkfrkqa rdilgidkde keeeeenpki
      361 eveplteeqk idqelqdlin kqkqkakrlk knanelkqke iirnqmnmlt dmnigieaaq
      421 igadslfnlk taektgqldk lakgkkkmif ndeelakdne ihideeeind ndkdsadeld
      481 elenqlddmy hqyqarkaer danyrakqar gdaddeawng ieednddves gkdyemeses
      541 dddddehirl iaekksngsl srtarnffas dsifnelsdd vileeienkt kgsngkmves
      601 iqeqvandnn enddgdndee esdfeivpnq ksddddddes mnsdddevst ttkstthqqk
      661 vdlatveamt lahqvalgqk nkydlidegi nrysfrdkdn lpdwfiddek khsklikpit
      721 keaaiaikek qkqlnarpik kvleaqsrkk lralkrleki kkksdlined sgkserdkad
      781 eisklmkkln kkqkqkpktt vvvargsnrg lsgrpkgvkg kykmvdgvmk neqralkria
      841 kkykk