E3 ubiquitin-protein ligase UBR1 isoform X1 [Drosophila

LOCUS       XP_070075352            1902 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_070075352
VERSION     XP_070075352.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070219251.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1902
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1902
                     /product="E3 ubiquitin-protein ligase UBR1 isoform X1"
                     /calculated_mol_wt=216067
     Region          162..230
                     /region_name="UBR-box_UBR1_like"
                     /note="UBR-box found in ubiquitin-protein ligases,
                     E3-alpha-1 (UBR1), E3-alpha-2 (UBR2), and similar
                     proteins; cd19672"
                     /db_xref="CDD:439070"
     Site            order(163,176,179,188,191,197,200,213,215,227,230)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:439070"
     Region          290..353
                     /region_name="ClpS"
                     /note="ATP-dependent Clp protease adaptor protein ClpS;
                     pfam02617"
                     /db_xref="CDD:460621"
     Region          1234..1292
                     /region_name="RING-H2_UBR1-like"
                     /note="RING finger, H2 subclass, found in
                     ubiquitin-protein ligase E3-alpha-1 (UBR1), E3-alpha-2
                     (UBR2), and similar proteins; cd16482"
                     /db_xref="CDD:438145"
     Region          1410..1878
                     /region_name="PRT6_C"
                     /note="Proteolysis_6 C-terminal; pfam18995"
                     /db_xref="CDD:465944"
     CDS             1..1902
                     /gene="Ubr1"
                     /coded_by="XM_070219251.1:419..6127"
                     /db_xref="GeneID:108062312"
ORIGIN      
        1 mdrydmedvv vappaecssp lkewrlkrqa gtlarsdfie ffkrespkyf dyqtggtetd
       61 tnaltrcrgv nymmggrhrv sqsdnlrigv lfqlthhhan lvpeikrlqq skqgpirgsl
      121 kcmfkealak eeiidvlvef mlgdnpasal eklrlegnta tvcgkvfkng eptyscrecg
      181 vdptcvlcvn cfkrsahrfh kykmstsggg gccdcgddea wkkdhycqlh lanrknples
      241 kiltdavler aeicfgaila fcvnyleiep naslqcldgn veggqvdgaq yctvlyndes
      301 htfdqviqtl tkiakckhkd ameivaaidr egravvkcdt fkecndlkta ienqmipata
      361 lltnprnnqs lrtsvlhiga vacqqfalql lgwfqeflvr hylfrktfae lvqrkqeafc
      421 irhileydvk lwktartcwh rllisgmlme ydnkmvlaqe fsrryative dfisddhdha
      481 fsivslsvql ftvpsiahhl iahegifdkl lhtfyhvaie kfiqnktlhf skniasltff
      541 kranyilydl ryllslkpel lnndlrsgfl egcralmrvl nvmqgmesit rqtgqhmdye
      601 pewecafnlh iklattisqv iewaagdvkl lrklykmtvr alvsnsfivg gektetrsva
      661 ghvanclmyd vsvkpvsihl plsrfyagiy lhlgahemty dslqteteal sikltpreii
      721 epvlcthami aqvaagmwrr ngysllhqly fyrnvrcrve mldrdivclq igaslmesne
      781 flihvlnkfn liawaqatye tmlaespvdd efmrqlsmid eflellivii gerwmpgvsm
      841 vteedrlrke iiqllctksy shselsralp dgnsgnsdni fedvintvav fkkpvgvesk
      901 gvyelkehlf eefnvyfyhy tkedkskaee lqrerrkakk qlvccpppml pqltpaftsm
      961 anilqcnvfl sictlvmera ldarsrsfte shlqkilhll gfaiqeelse hypflsfyer
     1021 sqhygilekl ddlarcprle ahrdfvvwti krykelqakq apsdsqpsgs qqcsggggas
     1081 eeqplsseeq arqekeirar laaerrakim aqmqsaqksf mksnaemfaa seketsgstg
     1141 amewedipae geeaaqddgq eqeqgavalr ptvvaclgpe rkiyqgsean fkcilcfenc
     1201 aisrsgpplv ssafvqtsrv ifttpnmrag psalhmsccg hvmhhscwqe yysneeskeq
     1261 rrphrnrval sqahnvefhc pycrtlsntv lpvtealpaf spapsasdsy lpldsfveim
     1321 rtlaadlgam rdeemcqfps vagilrksgv vgdmaqfers vqlirdppkl hanysdvmaf
     1381 lskallnarq sqqshlkeqq gtstgtatld pdsielvpll wdtcsytlqa leiylfevqk
     1441 plkaelpmrh qscainlvra csrfaasrcn felelgeipl spslrlqaey sarllneifn
     1501 qkgssvlewd cfrklvplqf gvlnlmtaes anqtvipsgs mfdfyilqtm flaqltkavl
     1561 cfdvdreqak rpghaeltql ayveqlpari rdnmvafyrr yniaarvlqa skqkqlaeeq
     1621 qkegdqqqqq ttvvipceph hlallleyvq rqmssflrca clfyrcltdi dfpdtfptdq
     1681 pdrfelmcqy lglepqlgvy fdmetvyatm mhsfashphi greieqrgqp eevrrclqle
     1741 pclrplprlk plyddysdli nsvsdifcpn nereemktpt mclicgsilc gqsyccqpel
     1801 gkmsvgacth hahacgaevg iflrirdcqv vylgrgkgcf vqppyldeyg etdqglrrgn
     1861 plrlcqaays riflqwlghg lheeiarlnd ntnvavtqwh hm