rho-associated protein kinase 2 isoform X3 [Drosophila takahashii].

LOCUS       XP_070075315            1235 aa            linear   INV 09-DEC-2024
ACCESSION   XP_070075315
VERSION     XP_070075315.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070219214.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1235
                     /product="rho-associated protein kinase 2 isoform X3"
                     /calculated_mol_wt=141534
     Region          <1..250
                     /region_name="Protein Kinases, catalytic domain"
                     /note="The protein kinase superfamily is mainly composed
                     of the catalytic domains of serine/threonine-specific and
                     tyrosine-specific protein kinases. It also includes RIO
                     kinases, which are atypical serine protein kinases,
                     aminoglycoside phosphotransferases; cl21453"
                     /db_xref="CDD:473864"
     Region          370..>936
                     /region_name="Smc"
                     /note="Chromosome segregation ATPase Smc [Cell cycle
                     control, cell division, chromosome partitioning]; COG1196"
                     /db_xref="CDD:440809"
     Region          692..763
                     /region_name="ROCK_SBD"
                     /note="Shroom-binding domain found in Rho-associated
                     coiled-coil containing protein kinase; cd22250"
                     /db_xref="CDD:409019"
     Site            order(693,696..697,699..700,703..704,706..707,710..711,
                     713..714,717..718,720..721,724..725,728,731)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:409019"
     Site            order(695,698..699,701..703,705..706,708..713,716)
                     /site_type="other"
                     /note="Shroom binding site [polypeptide binding]"
                     /db_xref="CDD:409019"
     Region          977..1093
                     /region_name="PH_ROCK"
                     /note="Rho-associated coiled-coil containing protein
                     kinase pleckstrin homology (PH) domain; cd01242"
                     /db_xref="CDD:269948"
     Region          1090..1153
                     /region_name="C1_ROCK"
                     /note="protein kinase C conserved region 1 (C1 domain)
                     found in the Rho-associated coiled-coil containing protein
                     kinase (ROCK) family; cd20813"
                     /db_xref="CDD:410363"
     CDS             1..1235
                     /gene="Rok"
                     /coded_by="XM_070219214.1:33..3740"
                     /db_xref="GeneID:108059116"
ORIGIN      
        1 mvmdfmpggd ivslmgdydi pekwaifytm evvlaldtih nmgfvhrdvk pdnmlldsyg
       61 hlkladfgtc mrmgangqvv ssnavgtpdy ispevlqsqg vdneygrecd wwsvgiflye
      121 mlfgetpfya dslvgtygki mdhknslsfp peveiseqak alirafltdr tqrlgrygie
      181 dikahpffrn dtwsfdnire svppvvpels sdddtrnfed ierdekpeev fpvpkgfdgn
      241 hlpfigftyt gdyqllssdt vdaeskeasa avnssgaasn nhghghghnh rhrpsnsnel
      301 krleallere rgrsealeqq daglrqqiel itkreaelqr iaseyekdla lrqhnykvam
      361 qkveqeielr kkteallvet qrnleneqkt rardlnindk vvslekqlle meqsyktete
      421 qtqrlkkhnt eldftvksqe ekvrdmvdmi dtlqkhkeel gqenaelqsl vvqeknlrsq
      481 lkelhkeaen kmqtlindie rtlgreqkaq ednralleki sdlekahagl dfelkaaqgr
      541 yqqevkahqe teksrlvsre eanlqevkal qsklneeksa rikadqhsqe kerqlsmlsv
      601 dyrqiqlrlq klegecrqes ekvaalqsql dqehskrnal lselslhsse vahlrsrenq
      661 lqkelgvqre akrrfeedlg qlkgthheal annrelqaql eaeqcfsrly ktqanenree
      721 saerlakied leeervslkh qvqvavarad sealarsiae etvadlekek tikelelkdf
      781 vmkhrneina keaalatlke aeielhkklg qkgvecedll qqhkkqqeel almrsskdee
      841 iaklldkckq evllkqvavn klaevmnrrd sdlpkqkska rstaelrkke kemrrlqqel
      901 sqerdkfnql llkhqdlqql caeeqqvkqk mvmeidckat eiehlqskln etaslssadn
      961 dpedsqhssl lsltqdsvfe gwlsvpnkqn rrrghgwkrq yvivssrkii fynsdidkhn
     1021 ttdavlildl skvyhvrsvt qgdviradak eiprifqlly agegashrpd eqsqldvsvl
     1081 hgnsneerpg tivhkghefv hityhmptac evcpkplwhm fkppaayeck rcrnkihkeh
     1141 vdkhdplapc klnhdprsar dmlllaatse eqslwvarll kriqksgyka nssnnnsstt
     1201 dgskispsqs trssykpyav nvqrsatlpa nsslk