serine/threonine-protein kinase tousled-like 1 isoform X6

LOCUS       XP_070075083            1277 aa            linear   INV 09-DEC-2024
            [Drosophila takahashii].
ACCESSION   XP_070075083
VERSION     XP_070075083.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070218982.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1277
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1277
                     /product="serine/threonine-protein kinase tousled-like 1
                     isoform X6"
                     /calculated_mol_wt=137341
     Region          <563..>699
                     /region_name="DUF5401"
                     /note="Family of unknown function (DUF5401); pfam17380"
                     /db_xref="CDD:375164"
     Region          949..1216
                     /region_name="STKc_TLK"
                     /note="Catalytic domain of the Serine/Threonine kinase,
                     Tousled-Like Kinase; cd13990"
                     /db_xref="CDD:270892"
     Site            order(952,965,967,1003,1020..1023,1027,1029,1068,1070,
                     1072..1073,1075,1089,1092,1115..1118)
                     /site_type="active"
                     /db_xref="CDD:270892"
     Site            order(1027,1029,1068,1070,1072,1092,1115..1118)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270892"
     Site            order(1088..1100,1105..1118)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270892"
     CDS             1..1277
                     /gene="Tlk"
                     /coded_by="XM_070218982.1:74..3907"
                     /db_xref="GeneID:108054955"
ORIGIN      
        1 mylsymsaga qlqmapqtts alshhhpnqq qqlqppqqqq aqppppqqqq hfanhhsaqq
       61 qsqqqqeqqn pqqaqqqqaq qqqilpqphl qhlhkhphql qlhqqqqqlh qqqqhfhqqq
      121 qqslqglhqg ssnpdsnmst gsshsekdvn dmlsgggaap gvaaaaaiqq qhpafapalg
      181 mqqppppppq hsnnggemgy ltagttttas vtavgkprtp aerkrkrkmp qtsadeagsg
      241 ggsggagaav vnnsslkgks lafrdmpkvn mslnlgdrlg gsagsgggag gagsggsgag
      301 sgsgsgggks arimlpvsdn kkindyfnkq qtgvgvgvpg gggaggntag lrgshtgggs
      361 kspssaqqqq qttqqqqqqa sgvatgggag gaaanqqvqv qtssayalyp paspqtqtpq
      421 qqqqqqpgad fhyvnsskaq qqqqqqqqrq qqqtsnqmvp phvvvglggh plslasiqqq
      481 qqtplsqqqq qqqqqqqqqq qqlgppttst asvvsthphq lgslgvvgmv gvgvgvgvnv
      541 gvgpplpppp pmampaaiit yskatqtevs lhelqereae hesgkvklde mtrlsdeqkc
      601 qivgnqktid qhkshiakci dvvkkllkek ssiekkearq kcmqnrlrlg qfvtqrvgat
      661 fqenwtdgya fqelsrrqee itaereeidr qkkqlmkkrp aesgrkrnnn snqnnqqqqq
      721 qqqhqqqqqq qnsnsndssq ltggvvtgpg sdrlggaagg vsvdsglggn nagaigggav
      781 gggvggggvg sggvggvggg ggrglsrsns tqanqaqllh nggggsggnv gnsggvgdrl
      841 sdrggggglg gndsgscsds gtflkpdpvs gaytaqeyye ydeilklrqn alkkedadlq
      901 lemeklerer nlhirelkri lnedqsrfnn hpvlndryll lmllgkggfs evhkafdlke
      961 qryvackvhq lnkdwkedkk anyikhalre ynihkaldhp rvvklydvfe idansfctvl
     1021 eycdghdldf ylkqhktipe rearsiimqv vsalkylnei kppvihydlk pgnilltegn
     1081 vcgeikitdf glskvmdden ynpdhgmdlt sqgagtywyl ppecfvvgkn ppkisskvdv
     1141 wsvgvifyqc lygkkpfghn qsqatileen tilkatevqf snkptvsnea ksfirgclay
     1201 rkedrmdvfa larheyiqpp ipkhgrgsln qqqqaqqqqq qqqqqqqqqs stsqanstgq
     1261 tsfsahmfgn mnqssss