neuronal acetylcholine receptor subunit alpha-7 isoform X3

LOCUS       XP_070074801             365 aa            linear   INV 09-DEC-2024
            [Drosophila takahashii].
ACCESSION   XP_070074801
VERSION     XP_070074801.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070218700.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..365
                     /product="neuronal acetylcholine receptor subunit alpha-7
                     isoform X3"
                     /calculated_mol_wt=41001
     Region          88..266
                     /region_name="LGIC_ECD_nAChR"
                     /note="extracellular domain of nicotinic acetylcholine
                     receptor; cd18997"
                     /db_xref="CDD:349798"
     Site            order(95,97,103..104,111,133,135,144..145,147,149..150,
                     154,156..157,161..163,165,175,177,179,183,205,266)
                     /site_type="other"
                     /note="pentamer interface [polypeptide binding]"
                     /db_xref="CDD:349798"
     Region          184..198
                     /region_name="Cys-loop"
                     /note="Cys-loop [structural motif]"
                     /db_xref="CDD:349798"
     Region          268..>330
                     /region_name="LGIC_TM_cation"
                     /note="transmembrane domain of Cys-loop
                     neurotransmitter-gated ion channels, includes 5HT3, nAChR,
                     and ZAC; cd19051"
                     /db_xref="CDD:349853"
     Region          268..292
                     /region_name="TM1 helix"
                     /note="TM1 helix [structural motif]"
                     /db_xref="CDD:349853"
     Region          300..321
                     /region_name="TM2 helix"
                     /note="TM2 helix [structural motif]"
                     /db_xref="CDD:349853"
     CDS             1..365
                     /gene="nAChRalpha7"
                     /coded_by="XM_070218700.1:246..1343"
                     /db_xref="GeneID:108066885"
ORIGIN      
        1 mkrqslsrrl dnlfcssqet nmsfpqphtl peapanggkm lvyglgllim ipactagphe
       61 krllhalldn ynslerpvvn esdplqlsfg ltlmqiidvd eknqllitni wlklewndmn
      121 lrwnssefgg vrdlripphr lwkpdvlmyn sadegfdgty atnvvvrnng sclyvppgif
      181 kstckiditw fpfddqrcem kfgswtydgf qldlqlqdea ggdissfitn gewdllgvpg
      241 krneiyyncc pepyiditfa ilirrktlyy ffnlivpcvl iasmallgft lppdsgekls
      301 lgvtillslt vflnmvaetm patsdavpll dksnipllvt lhiahaktrt gwlrmsaaal
      361 iiefi