rhophilin-2-A isoform X1 [Drosophila takahashii].

LOCUS       XP_070074756             725 aa            linear   INV 09-DEC-2024
ACCESSION   XP_070074756
VERSION     XP_070074756.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070218655.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..725
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..725
                     /product="rhophilin-2-A isoform X1"
                     /calculated_mol_wt=81259
     Region          40..124
                     /region_name="HR1_Rhophilin-1"
                     /note="Protein kinase C-related kinase homology region 1
                     (HR1) Rho-binding domain of Rhophilin-1; cd11633"
                     /db_xref="CDD:212023"
     Site            order(57,60,63..64,67..68,70..71,74..75,77..78,93..94,97,
                     100..101,104)
                     /site_type="other"
                     /note="putative Rho binding site 1 [polypeptide binding]"
                     /db_xref="CDD:212023"
     Site            order(65..66,68..69,72..73,75..76,79..80,88..89,91)
                     /site_type="other"
                     /note="putative Rho binding site 2 [polypeptide binding]"
                     /db_xref="CDD:212023"
     Region          128..523
                     /region_name="BRO1_Rhophilin"
                     /note="Protein-interacting Bro1-like domain of
                     RhoA-binding protein Rhophilin and related domains;
                     cd09244"
                     /db_xref="CDD:185767"
     Site            order(243,246,259,262..263,307,310..311,330,333..334,507,
                     509,511,513)
                     /site_type="other"
                     /note="putative ESCRT-III binding site"
                     /db_xref="CDD:185767"
     Region          585..649
                     /region_name="PDZ_canonical"
                     /note="canonical PDZ domain; cl49608"
                     /db_xref="CDD:483948"
     Site            order(585..590,598,601,630,634,637..638)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:467153"
     CDS             1..725
                     /gene="Rhp"
                     /coded_by="XM_070218655.1:116..2293"
                     /db_xref="GeneID:108056740"
ORIGIN      
        1 mfnlgamdgk tdelaqragk neeneddekl nelsfcfvrg sdpraatcrs klqnrrckln
       61 keinkelrlr agaenlykat snrklrdtva lelsfvnsnl qllkeqlael nssveiyqse
      121 shngimpmip lglketkein fmepfsdfil ehyseepsmy idaiadmtdt rqasktpsrd
      181 algvallfry yntlyyverr ffppdrnlgv yfewydsltg vpscqrtiaf ekactlfnlg
      241 giytqigarh drttergldl avdsflraag ifrhiydtft napsmdlkpq vldvlvslml
      301 sqareclfek lqlqieaigl sefscsdsqs frdlageaaq isheynemhk niqandthty
      361 lpecwaglvp vkaelykafa hfykarsida tdeikvsrnq dklstesfig nsqevesnfg
      421 tseeaatsna nklahlkeal asieeaqrlq rmcrylknks sltevmkevh sksqeeldrf
      481 rlqasannie egdllervve asskftlslt gpdftshkvk dpfkrlgpia ifsarrhwta
      541 prcvrlqkgs ssyhnvpann rcpldnddee hdggfnlyke efenfgfhvr gdapviiahv
      601 einsladlgg ikegdfivei agmdvkwysh qqvvqliqsc gsalelrvit pmdrnylkpl
      661 sskgslstls aasssgissg fpsptsiaak pklhlktsss sraagsvsss swnpfrrtps
      721 lakif