Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

rho GTPase-activating protein 190 isoform X5 [Drosophila


LOCUS       XP_070074636            1405 aa            linear   INV 09-DEC-2024
            takahashii].
ACCESSION   XP_070074636
VERSION     XP_070074636.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_070218535.1
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1405
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1405
                     /product="rho GTPase-activating protein 190 isoform X5"
                     /calculated_mol_wt=161567
     Region          <148..238
                     /region_name="P-loop containing Nucleoside Triphosphate
                     Hydrolases"
                     /note="Members of the P-loop NTPase domain superfamily are
                     characterized by a conserved nucleotide phosphate-binding
                     motif, also referred to as the Walker A motif
                     (GxxxxGK[S/T], where x is any residue), and the Walker B
                     motif (hhhh[D/E], where h is a...; cl38936"
                     /db_xref="CDD:476819"
     Site            190..193
                     /site_type="other"
                     /note="G4 box"
                     /db_xref="CDD:206648"
     Site            222..224
                     /site_type="other"
                     /note="G5 box"
                     /db_xref="CDD:206648"
     Region          254..333
                     /region_name="RhoGAP-FF1"
                     /note="p190-A and -B Rho GAPs FF domain; pfam16512"
                     /db_xref="CDD:465153"
     Region          599..749
                     /region_name="pseudoGTPaseD_p190RhoGAP"
                     /note="pseudoGTPase domain found in the family of
                     p190RhoGAP; cd22207"
                     /db_xref="CDD:412064"
     Region          1195..1395
                     /region_name="RhoGAP_p190"
                     /note="RhoGAP (GTPase-activator protein [GAP] for Rho-like
                     small GTPases) domain of p190-like proteins. p190, also
                     named RhoGAP5, plays a role in neuritogenesis and axon
                     branch stability. p190 shows a preference for Rho, over
                     Rac and Cdc42, and consists of an...; cd04373"
                     /db_xref="CDD:239838"
     Site            order(1230,1268,1272,1354,1357..1358,1386)
                     /site_type="other"
                     /note="putative GTPase interaction site [polypeptide
                     binding]"
                     /db_xref="CDD:239838"
     Site            1230
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:239838"
     CDS             1..1405
                     /gene="RhoGAPp190"
                     /coded_by="XM_070218535.1:26..4243"
                     /db_xref="GeneID:108056706"
ORIGIN      
        1 mrqfnisvig lsgtekdrgq vgvgksclcn rfmrpmaddy fidhisvlsq sdfsgrivnn
       61 dhflywgdvr ktteegveyq fniieqtefm ddstfqafkv gkmdpyskrc tatkvfsaek
      121 lmyicknqlg iekeyeqkvm pdgrlsidgf vvvfdvspvp nrsvekqvef vqnviatilk
      181 nkkplvlvtt knddayelyv reaekisqrk dykstvqlie tsahesinid laflllaqmi
      241 dkvknrvkii syqesaksrk elldtrseav trlirnqitd yhvlwsqgsk mlsqyrewne
      301 flnifgheag qklfrrhmkk lrddhlnkkl hqyldkfala leyllpdiga lnisdddawe
      361 carnylqnhi efeqyffecp qaswtelvdm deaedearip fdvletseae tvfrnylnsv
      421 qqdkkkigwk qqfkmllees gfvtpgkqls evrvlfmgre cfealsehdc qqiydihqdd
      481 iiekskqnfv elllehaqyf lqfknvdnit qedvrqitdv iqedsrykml drldqerrlm
      541 lvqhlrfihc pirdhcpffy ncvdslieev lsdksasnhk tpsnvggwkt sgsgsdrtln
      601 llivgsehla sdllndiric tgskgeyiye nqtyylnyri angdmeafka idvyssglic
      661 vysnqqsfet lkdnlertll cnleledkfe nlpivlvyqp qdlkenevey lrnegmrlse
      721 mlhcdfidht qnhqkyvydi lnivilslkl temksyepyp snhtdlrilc cifcgdqydi
      781 enivqplvae stlvkanehs iiidvfigda krrvefilss yhgtsqyrde lihgyiyfys
      841 akrrsslanl silaaqnani plqiiavtes ggvnaffnsd icqflitegn avadrfkgsf
      901 mtfsadqyvk fafynpflkt awdnkyeven lhveesitld sgegtlensv nqmprppprh
      961 esymlsntlg tdgsgsenye maptrslnsl neerdislde iyddnekpkh lhqnctesds
     1021 cassterrvr qqnayykans kkpvaakkqk kkkvaipvqt prvppfgsyv sppeiplhyq
     1081 rmvvgggggg gggpgekkkp epcvpdfmks dkspeysmvp elaaagifga enipeysakc
     1141 lkeyeklekl ekrrikeeta rlrklqekek eqekklkrkl kqnskglves aeaqfgklmi
     1201 sseqgeipif lnkcvefiek egldsegiyr vpgsrahvdm lfqrfeddtn teidaldipv
     1261 navatalkdf fskrlpplfs kdiikeleei agsrgvgnsk lnvevktdrs crlialksll
     1321 qklppinfai lkyifqhfvh vsdnsklnsm dsknlaicww ptlipidftd mghfeqlrpy
     1381 ledivqtmid qfpylfcgkd afvmv