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LOCUS XP_070074633 1587 aa linear INV 09-DEC-2024 takahashii]. ACCESSION XP_070074633 VERSION XP_070074633.1 DBLINK BioProject: PRJNA1194641 DBSOURCE REFSEQ: accession XM_070218532.1 KEYWORDS RefSeq. SOURCE Drosophila takahashii ORGANISM Drosophila takahashii Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_091683) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_030179915.1-RS_2024_12 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 12/07/2024 ##Genome-Annotation-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..1587 /organism="Drosophila takahashii" /strain="IR98-3 E-12201" /db_xref="taxon:29030" /chromosome="X" /sex="female" /tissue_type="Whole fly" /dev_stage="Adult fly" /collected_by="Originally obtained from EHIME-Fly" Protein 1..1587 /product="rho GTPase-activating protein 190 isoform X3" /calculated_mol_wt=180971 Region <148..238 /region_name="P-loop containing Nucleoside Triphosphate Hydrolases" /note="Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a...; cl38936" /db_xref="CDD:476819" Site 190..193 /site_type="other" /note="G4 box" /db_xref="CDD:206648" Site 222..224 /site_type="other" /note="G5 box" /db_xref="CDD:206648" Region 254..333 /region_name="RhoGAP-FF1" /note="p190-A and -B Rho GAPs FF domain; pfam16512" /db_xref="CDD:465153" Region 599..749 /region_name="pseudoGTPaseD_p190RhoGAP" /note="pseudoGTPase domain found in the family of p190RhoGAP; cd22207" /db_xref="CDD:412064" Region 1377..1577 /region_name="RhoGAP_p190" /note="RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and consists of an...; cd04373" /db_xref="CDD:239838" Site order(1412,1450,1454,1536,1539..1540,1568) /site_type="other" /note="putative GTPase interaction site [polypeptide binding]" /db_xref="CDD:239838" Site 1412 /site_type="active" /note="catalytic residue [active]" /db_xref="CDD:239838" CDS 1..1587 /gene="RhoGAPp190" /coded_by="XM_070218532.1:27..4790" /db_xref="GeneID:108056706" ORIGIN 1 mrqfnisvig lsgtekdrgq vgvgksclcn rfmrpmaddy fidhisvlsq sdfsgrivnn 61 dhflywgdvr ktteegveyq fniieqtefm ddstfqafkv gkmdpyskrc tatkvfsaek 121 lmyicknqlg iekeyeqkvm pdgrlsidgf vvvfdvspvp nrsvekqvef vqnviatilk 181 nkkplvlvtt knddayelyv reaekisqrk dykstvqlie tsahesinid laflllaqmi 241 dkvknrvkii syqesaksrk elldtrseav trlirnqitd yhvlwsqgsk mlsqyrewne 301 flnifgheag qklfrrhmkk lrddhlnkkl hqyldkfala leyllpdiga lnisdddawe 361 carnylqnhi efeqyffecp qaswtelvdm deaedearip fdvletseae tvfrnylnsv 421 qqdkkkigwk qqfkmllees gfvtpgkqls evrvlfmgre cfealsehdc qqiydihqdd 481 iiekskqnfv elllehaqyf lqfknvdnit qedvrqitdv iqedsrykml drldqerrlm 541 lvqhlrfihc pirdhcpffy ncvdslieev lsdksasnhk tpsnvggwkt sgsgsdrtln 601 llivgsehla sdllndiric tgskgeyiye nqtyylnyri angdmeafka idvyssglic 661 vysnqqsfet lkdnlertll cnleledkfe nlpivlvyqp qdlkenevey lrnegmrlse 721 mlhcdfidht qnhqkyvydi lnivilslkl temksyepyp snhtdlrilc cifcgdqydi 781 enivqplvae stlvkanehs iiidvfigda krrvefilss yhgtsqyrde lihgyiyfys 841 akrrsslanl silaaqnani plqiiavtes ggvnaffnsd icqflitegn avadrfkgsf 901 mtfsadqyvk fafynpflkt awdnkyeven lhveesitld sgegtlensv nqmprppprh 961 esymlsntlg tdgsgsenye maptrslnsl neerdislde iyddnekpkh lhqtdvsgsk 1021 dslathdaew ledksdgrrn mnknsiwnnf sgsthayttg rrhidsnlnk irpkgpsqtl 1081 kvgeapsrnc pamssstftl ptqqpgklnm knfqlvsdav akmnftgsgs gsgsgsgsgs 1141 tglglglgtg gsgsmadsyl epcdkdgkry dhaqldgede dseelaeyeq iyenedctes 1201 dscassterr vrqqnayyka nskkpvaakk qkkkkvaipv qtprvppfgs yvsppeiplh 1261 yqrmvvgggg gggggpgekk kpepcvpdfm ksdkspeysm vpelaaagif gaenipeysa 1321 kclkeyekle klekrrikee tarlrklqek ekeqekklkr klkqnskglv esaeaqfgkl 1381 misseqgeip iflnkcvefi ekegldsegi yrvpgsrahv dmlfqrfedd tnteidaldi 1441 pvnavatalk dffskrlppl fskdiikele eiagsrgvgn sklnvevktd rscrlialks 1501 llqklppinf ailkyifqhf vhvsdnskln smdsknlaic wwptlipidf tdmghfeqlr 1561 pyledivqtm idqfpylfcg kdafvmv