serine/threonine-protein kinase tousled-like 1 isoform X5

LOCUS       XP_044252043            1284 aa            linear   INV 09-DEC-2024
            [Drosophila takahashii].
ACCESSION   XP_044252043
VERSION     XP_044252043.1
DBLINK      BioProject: PRJNA1194641
DBSOURCE    REFSEQ: accession XM_044396108.2
KEYWORDS    RefSeq.
SOURCE      Drosophila takahashii
  ORGANISM  Drosophila takahashii
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091683) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_030179915.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/07/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Drosophila takahashii"
                     /strain="IR98-3 E-12201"
                     /db_xref="taxon:29030"
                     /chromosome="X"
                     /sex="female"
                     /tissue_type="Whole fly"
                     /dev_stage="Adult fly"
                     /collected_by="Originally obtained from EHIME-Fly"
     Protein         1..1284
                     /product="serine/threonine-protein kinase tousled-like 1
                     isoform X5"
                     /calculated_mol_wt=138200
     Region          <570..>706
                     /region_name="DUF5401"
                     /note="Family of unknown function (DUF5401); pfam17380"
                     /db_xref="CDD:375164"
     Region          956..1223
                     /region_name="STKc_TLK"
                     /note="Catalytic domain of the Serine/Threonine kinase,
                     Tousled-Like Kinase; cd13990"
                     /db_xref="CDD:270892"
     Site            order(959,972,974,1010,1027..1030,1034,1036,1075,1077,
                     1079..1080,1082,1096,1099,1122..1125)
                     /site_type="active"
                     /db_xref="CDD:270892"
     Site            order(1034,1036,1075,1077,1079,1099,1122..1125)
                     /site_type="other"
                     /note="polypeptide substrate binding site [polypeptide
                     binding]"
                     /db_xref="CDD:270892"
     Site            order(1095..1107,1112..1125)
                     /site_type="other"
                     /note="activation loop (A-loop)"
                     /db_xref="CDD:270892"
     CDS             1..1284
                     /gene="Tlk"
                     /coded_by="XM_044396108.2:627..4481"
                     /db_xref="GeneID:108054955"
ORIGIN      
        1 mcvqknmrrl kkmsagaqlq mapqttsals hhhpnqqqql qppqqqqaqp pppqqqqhfa
       61 nhhsaqqqsq qqqeqqnpqq aqqqqaqqqq ilpqphlqhl hkhphqlqlh qqqqqlhqqq
      121 qhfhqqqqqs lqglhqgssn pdsnmstgss hsekdvndml sgggaapgva aaaaiqqqhp
      181 afapalgmqq ppppppqhsn nggemgylta gttttasvta vgkprtpaer krkrkmpqts
      241 adeagsgggs ggagaavvnn sslkgkslaf rdmpkvnmsl nlgdrlggsa gsgggaggag
      301 sggsgagsgs gsgggksari mlpvsdnkki ndyfnkqqtg vgvgvpgggg aggntaglrg
      361 shtgggsksp ssaqqqqqtt qqqqqqasgv atgggaggaa anqqvqvqts sayalyppas
      421 pqtqtpqqqq qqqpgadfhy vnsskaqqqq qqqqqrqqqq tsnqmvpphv vvglgghpls
      481 lasiqqqqqt plsqqqqqqq qqqqqqqqql gppttstasv vsthphqlgs lgvvgmvgvg
      541 vgvgvnvgvg pplpppppma mpaaiitysk atqtevslhe lqereaehes gkvkldemtr
      601 lsdeqkcqiv gnqktidqhk shiakcidvv kkllkekssi ekkearqkcm qnrlrlgqfv
      661 tqrvgatfqe nwtdgyafqe lsrrqeeita ereeidrqkk qlmkkrpaes grkrnnnsnq
      721 nnqqqqqqqq hqqqqqqqns nsndssqltg gvvtgpgsdr lggaaggvsv dsglggnnag
      781 aigggavggg vggggvgsgg vggvgggggr glsrsnstqa nqaqllhngg ggsggnvgns
      841 ggvgdrlsdr ggggglggnd sgscsdsgtf lkpdpvsgay taqeyyeyde ilklrqnalk
      901 kedadlqlem eklerernlh irelkrilne dqsrfnnhpv lndrylllml lgkggfsevh
      961 kafdlkeqry vackvhqlnk dwkedkkany ikhalreyni hkaldhprvv klydvfeida
     1021 nsfctvleyc dghdldfylk qhktiperea rsiimqvvsa lkylneikpp vihydlkpgn
     1081 illtegnvcg eikitdfgls kvmddenynp dhgmdltsqg agtywylppe cfvvgknppk
     1141 isskvdvwsv gvifyqclyg kkpfghnqsq atileentil katevqfsnk ptvsneaksf
     1201 irgclayrke drmdvfalar heyiqppipk hgrgslnqqq qaqqqqqqqq qqqqqqssts
     1261 qanstgqtsf sahmfgnmnq ssss